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首页> 外文期刊>Genetics, selection, evolution >Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations
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Cytogenetic and molecular characterization of eight new reciprocal translocations in the pig species. Estimation of their incidence in French populations

机译：猪中八个新的易位易位的细胞遗传学和分子表征。估计其在法国人群中的发病率

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摘要

Eight new cases of reciprocal translocation in the domestic pig are described. All the rearrangements were highlighted using GTG banding techniques. Chromosome painting experiments were also carried out to confirm the proposed hypotheses and to accurately locate the breakpoints. Three translocations, rcp(4;6)(q21;p14), rcp(2;6)(p17;q27) and rcp(5;17)(p12;q13) were found in boars siring small litters (8.3 and 7.4 piglets born alive per litter, on average, for translocations 2/6 and 5/17, respectively). The remaining five, rcp(5;8)(p12;q21), rcp(15;17)(q24;q21), rcp(7;8)(q24;p21), rcp(5;8)(p11;p23) and rcp(3;15)(q27;q13) were identified in young boars controlled before entering reproduction. A decrease in prolificacy of 22% was estimated for the 3/15 translocation after reproduction of the boar carrier. A parental origin by inheritance of the translocation was established for the (5;8)(p11;p23) translocation. The overall incidence of reciprocal translocations in the French pig populations over the 2000/2001 period was estimated (0.34%).
机译：描述了家猪中的8个新的相互易位病例。使用GTG绑定技术突出显示了所有重排。还进行了染色体绘画实验，以确认提出的假设并准确定位断点。在小窝的公猪中发现了三个易位rcp（4; 6）（q21; p14），rcp（2; 6）（p17; q27）和rcp（5; 17）（p12; q13）平均每胎活产2/6和5/17）。其余五个分别为rcp（5; 8）（p12; q21），rcp（15; 17）（q24; q21），rcp（7; 8）（q24; p21），rcp（5; 8）（p11; p23 ）和rcp（3; 15）（q27; q13）在进入繁殖之前被控制的年轻公猪中鉴定出。估计公猪载体繁殖后3/15易位的繁殖力下降了22％。通过（5; 8）（p11; p23）易位建立了通过易位遗传而产生的亲本。估计2000/2001年期间法国猪种群中相互易位的总体发生率（0.34％）。

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