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首页> 外文期刊>Bioinformatics and Biology Insights >An Improved Approach for Mapping Quantitative Trait Loci in a Pseudo-Testcross: Revisiting a Poplar Mapping Study
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An Improved Approach for Mapping Quantitative Trait Loci in a Pseudo-Testcross: Revisiting a Poplar Mapping Study

机译：伪测交中数量性状基因座定位的一种改进方法：重新研究杨树定位研究

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摘要

A pseudo-testcross pedigree is widely used for mapping quantitative trait loci (QTL) in outcrossing species, but the model for analyzing pseudo-testcross data borrowed from the inbred backcross design can only detect those QTLs that are heterozygous only in one parent. In this study, an intercross model that incorporates the high heterozygosity and phase uncertainty of outcrossing species was used to reanalyze a published data set on QTL mapping in poplar trees. Several intercross QTLs that are heterozygous in both parents were detected, which are responsible not only for biomass traits, but also for their genetic correlations. This study provides a more complete identification of QTLs responsible for economically important biomass traits in poplars.
机译：伪-testcross谱系被广泛用于绘制异种的数量性状基因座（QTL），但是从近交回交设计中借来的伪-testcross数据分析模型只能检测那些仅在一个亲本中杂合的QTL。在这项研究中，采用了具有较高杂合度和异质性的相交不确定性的杂交模型来重新分析已发表的关于杨树中QTL定位的数据集。检测到在父母双方中都是杂合的几个交叉的QTL，这不仅与生物量性状有关，而且还与它们的遗传相关性有关。这项研究提供了对杨树中具有重要经济意义的生物量性状的QTL的更完整鉴定。

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