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Setting health research priorities using the CHNRI method: VII. A review of the first 50 applications of the CHNRI method

机译：使用CHNRI方法确定健康研究重点：VII。回顾CHNRI方法的前50个应用

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Background Several recent reviews of the methods used to set research priorities have identified the CHNRI method (acronym derived from the “Child Health and Nutrition Research Initiative”) as an approach that clearly became popular and widely used over the past decade. In this paper we review the first 50 examples of application of the CHNRI method, published between 2007 and 2016, and summarize the most important messages that emerged from those experiences. Methods We conducted a literature review to identify the first 50 examples of application of the CHNRI method in chronological order. We searched Google Scholar, PubMed and so–called grey literature. Results Initially, between 2007 and 2011, the CHNRI method was mainly used for setting research priorities to address global child health issues, although the first cases of application outside this field (eg, mental health, disabilities and zoonoses) were also recorded. Since 2012 the CHNRI method was used more widely, expanding into the topics such as adolescent health, dementia, national health policy and education. The majority of the exercises were focused on issues that were only relevant to low– and middle–income countries, and national–level applications are on the rise. The first CHNRI–based articles adhered to the five recommended priority–setting criteria, but by 2016 more than two–thirds of all conducted exercises departed from recommendations, modifying the CHNRI method to suit each particular exercise. This was done not only by changing the number of criteria used, but also by introducing some entirely new criteria (eg, “low cost”, “sustainability”, “acceptability”, “feasibility”, “relevance” and others). Conclusions The popularity of the CHNRI method in setting health research priorities can be attributed to several key conceptual advances that have addressed common concerns. The method is systematic in nature, offering an acceptable framework for handling many research questions. It is also transparent and replicable, because it clearly defines the context and priority–setting criteria. It is democratic, as it relies on “crowd–sourcing”. It is inclusive, fostering “ownership” of the results by ensuring that various groups invest in the process. It is very flexible and adjustable to many different contexts and needs. Finally, it is simple and relatively inexpensive to conduct, which we believe is one of the main reasons for its uptake by many groups globally, particularly those in low– and middle–income countries.
机译：背景技术最近对用于设定研究重点的方法的一些评论已经确定，CHNRI方法（源自“儿童健康与营养研究计划”的缩写）显然已在过去十年中流行并广泛使用。在本文中，我们回顾了2007年至2016年间发布的CHNRI方法应用的前50个示例，并总结了从这些经验中得出的最重要的信息。方法我们进行了文献综述，以按时间顺序确定了CHNRI方法应用的前50个实例。我们搜索了Google Scholar，PubMed和所谓的灰色文献。结果最初，在2007年至2011年之间，虽然也记录了该领域以外的首例应用（例如，精神健康，残疾和人畜共患病），但CHNRI方法主要用于确定研究优先级以解决全球儿童健康问题。自2012年以来，CHNRI方法得到了更广泛的使用，并扩展到诸如青少年健康，痴呆，国家卫生政策和教育等主题。大多数练习都集中在仅与低收入和中等收入国家有关的问题上，并且在国家层面的应用正在增加。基于CHNRI的第一篇文章遵循了建议的五项优先级确定标准，但到2016年，所有进行的练习中有三分之二以上均偏离了建议，并修改了CHNRI方法以适合每个特定练习。这不仅是通过更改所使用标准的数量来实现的，而且还通过引入一些全新的标准来实现（例如，“低成本”，“可持续性”，“可接受性”，“可行性”，“相关性”等）。结论CHNRI方法在设定健康研究优先领域方面的普及可以归因于解决了共同关注点的几个关键概念性进展。该方法本质上是系统的，为处理许多研究问题提供了可接受的框架。它也是透明和可复制的，因为它明确定义了上下文和优先级设置标准。它是民主的，因为它依赖于“众包”。它具有包容性，可以通过确保各个小组对流程进行投资来促进结果的“所有权”。它非常灵活，可以根据许多不同的上下文和需求进行调整。最后，它的操作简单且相对便宜，我们认为这是全球许多团体（尤其是中低收入国家的团体）采用该程序的主要原因之一。

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