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A case of mesothelioma masquerading pre-operatively as ovarian cancer and brief review of the literature

机译:术前伪装成卵巢癌的间皮瘤一例并文献复习

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Background Malignant peritoneal mesothelioma (MPM) can masquerade as an ovarian epithelial neoplasm, with very similar presenting clinical symptoms and imaging findings. The gold standard in differentiating between these two diagnoses lies in tissue pathology. Case report This is a case of MPM that was initially misdiagnosed as ovarian cancer based on family history, imaging, and surgical findings. Tissue diagnosis preoperatively would have changed the planned procedure. Retrospectively, after the diagnosis of MPM, the patient was found to have had an indirect exposure to asbestos through her father. Conclusions This case highlights the importance of keeping a broad differential when diagnosing ovarian malignancies, collecting both family and social histories (including screening for exposure to asbestos), and the benefit of obtaining tissue diagnosis when MPM is suspected. Highlights ? Malignant peritoneal mesothelioma can masquerade as ovarian epithelial neoplasm. ? Due to similar presenting clinical symptoms, differential diagnosis can be difficult. ? The key to differentiating between these two diagnoses lies in tissue pathology. ? Family, social, and occupational exposure histories are crucial if suspected ovarian malignancy ? Importance of considering broad differential when ovarian malignancy is suspected.
机译:背景恶性腹膜间皮瘤(MPM)可以伪装成卵巢上皮肿瘤,具有非常相似的临床症状和影像学表现。区分这两种诊断的金标准在于组织病理学。病例报告这是一例MPM,最初根据家族病史,影像学和手术结果被误诊为卵巢癌。术前组织诊断将改变计划的程序。回顾性地,在诊断出MPM之后,发现该患者通过其父亲间接接触了石棉。结论该病例强调了在诊断卵巢恶性肿瘤,收集家庭和社会历史(包括筛查石棉暴露情况)时保持广泛差异的重要性,以及怀疑MPM时获得组织诊断的益处。强调 ?恶性腹膜间皮瘤可伪装成卵巢上皮肿瘤。 ?由于出现类似的临床症状,可能难以进行鉴别诊断。 ?区分这两种诊断的关键在于组织病理学。 ?如果怀疑卵巢恶性,家庭,社会和职业接触史至关重要。当怀疑卵巢恶性肿瘤时,考虑广泛性差异的重要性。

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