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Management of a rapidly enlarging new adnexal mass: a rare case of desmoplastic small round cell tumor of the ovary arising in pregnancy

机译:快速增加的新附件肿块的处理:在妊娠中发生的卵巢卵巢增生性小圆形细胞瘤的罕见病例

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Background Desmoplastic small round cell tumor (DSRCT) is an extremely rare sarcomatous tumor, which is most commonly seen in men. Clinicians managing a patient with a rapidly enlarging mass in pregnancy should be aware of the risk for malignancy. Case A 31-year-old woman was found to have a newly enlarged ovarian mass in the second trimester. She subsequently underwent a laparotomy for removal, with chemotherapy for presumed poorly differentiated ovarian malignancy. Ultimately she was diagnosed with a desmoplastic small round cell tumor of the ovary and had progression at time of delivery. Following cesarean delivery, she had a tumor reductive surgery. She has completed 12 cycles of intensive chemotherapy and is alive with disease at 14 months. Conclusion Care should be taken not to delay evaluation of a rapidly enlarging mass in pregnancy. While this tumor type is extremely rare, a malignancy in pregnancy must be ruled out in this clinical scenario. Highlights ? Rapidly enlarging mass in pregnancy is of high concern for malignancy. ? Surgical management of complex mass in pregnancy is safe and technically feasible. ? Chemotherapy is an option once a tissue diagnosis has been made. ? While rare, sarcomas in pregnancy can develop and grow rapidly.
机译:背景增生性小圆形细胞瘤(DSRCT)是一种极为罕见的肉瘤性肿瘤,在男性中最为常见。处理妊娠迅速增大的患者的临床医生应意识到恶性肿瘤的风险。病例发现一名31岁妇女在孕中期有新的卵巢肿块。随后,她进行了剖腹手术以切除卵巢,并因其推测为低分化的卵巢恶性肿瘤而接受了化疗。最终,她被诊断出患有卵巢增生性小圆形细胞瘤,并在分娩时进展。剖宫产后,她进行了肿瘤缩小手术。她已经完成了12个周期的强化化疗,并且在14个月时还活着。结论应注意不要延迟评估妊娠迅速增大的肿块。尽管这种肿瘤类型极为罕见,但在这种临床情况下必须排除妊娠恶性肿瘤。强调 ?妊娠期迅速增大的肿块是恶性肿瘤的高度关注。 ?妊娠期复杂肿块的手术管理是安全的,在技术上也是可行的。 ?一旦做出了组织诊断,就可以选择化学疗法。 ?虽然很少见,但妊娠中的肉瘤可以迅速发展。

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