首页>
外文期刊>Gynecologic Oncology Reports
>Serous carcinoma of endometrium in combination with neuroendocrine small-cell: A case report and literature review
【24h】
Serous carcinoma of endometrium in combination with neuroendocrine small-cell: A case report and literature review
Endometrial serous carcinomas are very clinically aggressive, which constitutes 40% of all deaths and recurrences associated with endometrial cancer. Small-cell carcinoma of the endometrium is relatively rare but aggressive, and often presents a component of endometrioid carcinoma, and is not generally associated with serous carcinoma. Herein, we report a case of 74-year-old African-American female, who presented with intermittent post-menopausal bleeding for 1-month. She underwent robotic-assisted laparoscopic hysterectomy, bilateral salpingo-oophorectomy, sentinel lymph node mapping, and pelvic-and-aortic lymphadenectomy. Final pathology was consistent with serous carcinoma of the endometrium in combination with neuroendocrine small-cell carcinoma. This extremely rare combination of tumors presents a challenge for treatment. The mainstay of treatment seems to be surgery followed by chemotherapy ± radiation therapy. To our knowledge, it represents an under-reported area of gynecological medicine. Highlights ? Small-cell carcinoma of endometrium is rare but aggressive and challenging to care. ? We report a case presenting with intermittent post-menopausal bleeding for 1-month. ? She underwent robotic hysterectomy, BSO, SLN mapping, and complete lymphadenectomy. ? Pathology revealed serous carcinoma of endometrium combined with neuroendocrine SCC. ? To our knowledge, it represents an under-reported area of gynecological medicine.
展开▼
