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Ovarian yolk sac tumor coexisting with epithelial ovarian cancer: An aggressive rare entity

机译:卵巢卵黄囊肿瘤与上皮性卵巢癌共存:侵略性罕见实体

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Yolk sac tumor (YST) is the second most common subtype of ovarian germ cell tumors. It usually occurs in the second and third decades of life and is rare in postmenopausal women. In postmenopausal women, YST is commonly an aggressive tumor and can present as a pure germ cell component or as a mixed component with other germ cell or epithelial components. The recognition of this histological subtype is important not only for differential diagnosis but also for determining prognosis and treatment decisions. In this case report, we describe a 61-year-old woman with YST coexisting with epithelial carcinoma focusing on the efficacy of systemic therapies. Highlights ? Yolk sac tumor (YST) is an aggressive common type of ovarian germ cell tumor. ? YST commonly occurs in premenopausal women and is rare in postmenopausal women. ? YST is commonly pure and rarely coexists with an epithelial component. ? The coexistence of histologic subtypes is associated with an aggressive outcome. ? Treatments are surgery and chemotherapy for the adjuvant and metastatic setting.
机译:卵黄囊肿瘤(YST)是卵巢生殖细胞肿瘤的第二大最常见亚型。它通常发生在生命的第二和第三十年,在绝经后的女性中很少见。在绝经后妇女中,YST通常是一种侵袭性肿瘤,可以纯生殖细胞成分或与其他生殖细胞或上皮成分的混合成分存在。这种组织学亚型的识别不仅对于鉴别诊断很重要,对于确定预后和治疗决策也很重要。在此病例报告中,我们描述了一名61岁的YST与上皮癌并存的女性,重点研究了全身疗法的疗效。强调 ?卵黄囊肿瘤(YST)是一种侵袭性的卵巢生殖细胞肿瘤。 ? YST通常发生在绝经前的女性中,在绝经后的女性中很少见。 ? YST通常是纯净的,很少与上皮成分共存。 ?组织学亚型的共存与积极的结果相关。 ?治疗方法是通过手术和化疗辅助和转移。

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