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首页> 外文期刊>eNeurologicalSci >Extensive necrotizing lymphadenitis complicated by an aseptic meningeal reaction
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Extensive necrotizing lymphadenitis complicated by an aseptic meningeal reaction

机译：广泛性坏死性淋巴结炎并发无菌性脑膜反应

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Subacute necrotizing lymphadenitis (SNL), also known as Kikuchidisease (named after the finder of this syndrome [1]), is an inflammatory disease seen in adolescents and young adults. Masahiro Kikuchiestablished the clinical entity of SNL, which is pathologically characterized as histiocytic inflammatory lymphadenitis without the infiltrationof neutrophils. A majority of the cases involve the cervical lymphnodes and occur in young female adults. SNL is well-known as a selflimiting pathogenesis which generally does not require any specifictreatment. Although there is much speculation about the cause of SNL,a viral or autoimmune reaction has been proposed [2]. The diseaseetiology is thought to be associated with an HLA class II disparity(DPA1*01 and DPB1*0202), because the accumulation of this diseaseis apparent among Asian people including Japanese [3].
机译：亚急性坏死性淋巴结炎（SNL），也称为菊苣病（以该综合征的发现者命名[1]），是一种在青少年和年轻人中常见的炎性疾病。 Masahiro Kikuchi建立了SNL的临床实体，其病理特征是组织细胞炎性淋巴结炎，而没有嗜中性白细胞的浸润。大多数病例涉及子宫颈淋巴结并且发生在年轻的成年女性中。 SNL是众所周知的一种自限性发病机制，通常不需要任何特殊治疗。尽管人们对SNL的病因有很多猜测，但已提出了病毒或自身免疫反应[2]。人们认为该病因与HLA II类差异（DPA1 * 01和DPB1 * 0202）有关，因为这种疾病的累积在包括日本人在内的亚洲人中很明显[3]。

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