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首页> 外文期刊>eNeurologicalSci >Disregard of neurological impairments associated with neglected tropical diseases in Africa
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Disregard of neurological impairments associated with neglected tropical diseases in Africa

机译：忽视与非洲被忽视的热带病有关的神经功能障碍

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Neglected tropical diseases (NTDs) affect people in the bottom billion poorest in the world. These diseases are concentrated in rural areas, conflict zones and urban slums in Africa and other tropical areas. While the World Health Organization recognizes seventeen priority NTDs, the list of conditions present in Africa and elsewhere that are eligible to be classified as NTDs is much longer. Although NTDs are generally marginalized, their associated neurological burden has been almost completely disregarded. However, reports indicate that trichuriasis, schistosomiasis and hookworm infection, among others, cause impairments in memory and cognition, negatively affecting school attendance rates and educational performance particularly among children, as well as agricultural productivity among adults. Consequently, the neurological impairments have substantial influence on education and economic productivity, thus aggravating and perpetuating poverty in affected societies. However, inadequate research, policy and public health attention has been paid to the neurological burdens associated with NTDs. In order to appropriately address these burdens, we recommend the development of policy interventions that focus on the following areas: (i) the introduction of training programs to develop the capacity of scientists and clinicians in research, diagnostic and treatment approaches (ii) the establishment of competitive research grant schemes to fund cutting-edge research into these neurological impairments, and (iii) the development of public health interventions to improve community awareness of the NTD-associated neurological problems, possibly enhancing disease prevention and expediting treatment. Highlights ? Neglected tropical diseases (NTDs) disproportionately affect the world’s poorest populations ? While NTDs are generally marginalized, their associated neurological burden is almost completely disregarded in Africa ? Neurological impairments of NTDs disrupt cognition and memory, thus adversely impacting education and health of affected families. ? Policy interventions focused on advancing clinical research and early diagnosis and treatment paradigms are encouraged.
机译：被忽视的热带病（NTDs）影响着世界上最底层的十亿最贫困人口。这些疾病集中在非洲和其他热带地区的农村地区，冲突地区和城市贫民窟。尽管世界卫生组织承认17个优先NTD，但非洲和其他地区存在的可归类为NTD的条件清单要长得多。尽管NTD通常被边缘化，但是其相关的神经系统负担却几乎被完全忽略了。但是，报告表明，滴虫病，血吸虫病和钩虫感染等会导致记忆力和认知能力下降，特别是对儿童的入学率和教育成绩以及成人的农业生产率产生负面影响。因此，神经功能障碍对教育和经济生产力具有重大影响，从而使受影响社会的贫困加剧并长期存在。但是，对于与NTD相关的神经系统负担，研究，政策和公共卫生关注不足。为了适当地解决这些负担，我们建议制定针对以下领域的政策干预措施：（i）引入培训计划，以提高科学家和临床医生在研究，诊断和治疗方法方面的能力（ii）建立竞争性研究补助金计划，以资助对这些神经系统损害的前沿研究;（iii）制定公共卫生干预措施，以提高社区对与NTD相关的神经系统问题的认识，并可能加强疾病预防和加快治疗。强调 ？被忽视的热带病（NTDs）对世界上最贫穷的人口造成了不成比例的影响？虽然NTD通常被边缘化，但在非洲，它们相关的神经系统负担几乎被完全忽略了吗？ NTD的神经功能障碍会破坏认知和记忆，从而对受影响家庭的教育和健康产生不利影响。 ？鼓励着重于促进临床研究和早期诊断及治疗范例的政策干预措施。

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