...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Gynecological surgery >Total laparoscopic hysterectomy versus total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial carcinoma: a randomised controlled trial with 5-year follow-up
【24h】

Total laparoscopic hysterectomy versus total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial carcinoma: a randomised controlled trial with 5-year follow-up

机译：全腹腔镜子宫切除术与全腹子宫切除术联合双侧输卵管卵巢切除术治疗子宫内膜癌：5年随访的随机对照试验

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

This report is on recovery and long-term outcomes in a small-scale randomised controlled trial (RCT) after total laparoscopic hysterectomy versus total abdominal hysterectomy in (potential) endometrial carcinoma patients. An RCT was performed among women with atypical endometrial hyperplasia and endometrial carcinoma scheduled for hysterectomy in a teaching hospital in The Netherlands. Women were randomised to total laparoscopic hysterectomy versus total abdominal hysterectomy both with bilateral salpingo-oophorectomy and were followed until 5?years after the intervention. Patients completed the RAND 36-Item Short Form Health Survey (RAND-36), Quality of Recovery-40 (QoR-40) and Recovery Index-10 (RI-10) until 12?weeks after surgery. Main outcome measure was quality of life and recovery in the first 12?weeks after surgery. A linear mixed model was used for statistical analysis while accounting for baseline values where applicable. Seventeen women were included, of whom 11 allocated to the laparoscopic arm and 6 to the abdominal arm. Laparoscopic hysterectomy performed better on all scales and subscales used in the study. A statistically significant treatment effect, favouring laparoscopic hysterectomy, was found in the total RAND-36 (difference between groups 142 units, 95% confidence interval 46; 236). Clinical follow-up was completed after median 60?months, but this study was too small for conclusions regarding the safety and survival. Laparoscopic hysterectomy results in better postoperative quality of life in the first 12?weeks after surgery when compared with abdominal hysterectomy.
机译：这份报告是关于（潜在）子宫内膜癌患者全腹腔镜子宫切除术与全腹子宫切除术后的小型随机对照试验（RCT）的恢复和长期结果的。在荷兰的一家教学医院对患有非典型子宫内膜增生和子宫内膜癌的妇女行子宫切除术进行了RCT。将女性随机分为双侧输卵管卵巢切除术和全腹腔镜子宫切除术与全腹子宫切除术，并随访至干预后5年。患者在手术后12周之前完成了RAND 36项简短健康调查（RAND-36），恢复质量40（QoR-40）和恢复指数10（RI-10）。主要结局指标是术后头12周的生活质量和恢复情况。使用线性混合模型进行统计分析，同时在适用时考虑基线值。其中包括十七名妇女，其中有十一名分配给腹腔镜臂，六名分配给腹臂。腹腔镜子宫切除术在本研究中使用的所有规模和亚规模上均表现更好。在总的RAND-36中发现了统计学上显着的治疗效果，有利于腹腔镜子宫切除术（组间142个单位之间的差异，95％置信区间46; 236）。中位60个月后完成了临床随访，但是该研究规模太小，无法得出有关安全性和生存率的结论。与腹腔子宫切除术相比，腹腔镜子宫切除术可在术后头12周提高术后生活质量。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号