Effects of Neuroendocrine CB1 Activity on Adult Leydig Cells

Gilda Cobellis; Rosaria Meccariello; Rosanna Chianese; Teresa Chioccarelli; Silvia Fasano; Riccardo Pierantoni

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Effects of Neuroendocrine CB1 Activity on Adult Leydig Cells

机译：神经内分泌CB1活性对成年Leydig细胞的影响

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Endocannabinoids control male reproduction acting at central and local level via cannabinoid receptors. The cannabinoid receptor CB1 has been characterized in the testis, in somatic and germ cells of mammalian and non-mammalian animal models, and its activity related to Leydig cell differentiation, steroidogenesis, spermiogenesis, sperm quality, and maturation. In this short review, we provide a summary of the insights concerning neuroendocrine CB1 activity in male reproduction focusing on adult Leydig cell ontogenesis and steroid biosynthesis.

机译：内源性大麻素通过大麻素受体控制男性在中央和局部水平上的繁殖。大麻素受体CB1已在哺乳动物和非哺乳动物模型的体细胞和生殖细胞的睾丸中进行了表征，其活性与Leydig细胞分化，类固醇生成，精子生成，精子质量和成熟有关。在这篇简短的评论中，我们提供了关于成年莱迪克细胞本体发生和类固醇生物合成的男性生殖中神经内分泌CB1活性的见解的摘要。

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《Frontiers in Endocrinology》 |2016年第2期|共4页
作者
Gilda Cobellis; Rosaria Meccariello; Rosanna Chianese; Teresa Chioccarelli; Silvia Fasano; Riccardo Pierantoni;
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中图分类内分泌腺疾病及代谢病;
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1. Effects of Neuroendocrine CB1 Activity on Adult Leydig Cells [J] . Cobellis, Gilda Frontiers in Endocrinology . 2016,第1期

机译：神经内分泌CB1活性对成年Leydig细胞的影响
2. In vitro effects of gonadotropin-releasing hormone (GnRH) on Leydig cells of adult alpaca (Lama pacos) testis: GnRH receptor immunolocalization, testosterone and prostaglandin synthesis, and cyclooxygenase activities [J] . Zerani M., Catone G., Quassinti L., Domestic Animal Endocrinology . 2011,第1期

机译：促性腺激素释放激素（GnRH）对成年羊驼（Lama pacos）睾丸间质细胞的体外影响：GnRH受体的免疫定位，睾丸激素和前列腺素的合成以及环氧合酶的活性
3. The increased number of Leydig cells by di(2-ethylhexyl) phthalate comes from the differentiation of stem cells into Leydig cell lineage in the adult rat testis [J] . GuoJ., LiX.-W., LiangY., Toxicology: An International Journal Concerned with the Effects of Chemicals on Living Systems . 2013,第Null期

机译：邻苯二甲酸二（2-乙基己基）酯增加的Leydig细胞数量来自成年大鼠睾丸中干细胞向Leydig细胞谱系分化的过程
4. The effects of perfluorooctane sulfonate(PFOS) on proliferation of mouse leydig cells in vitro [C] . Zhang De-yong, Xu Xiao-lu, Shen Xiu-ying International Conference on Energy and Environmental Protection . 2013

机译：全氟辛烷磺酸盐（PFOS）对体外小鼠Leydig细胞增殖的影响
5. Leydig cell stem/precursor cells in neonatal, adult and aged testes [D] . Stanley, Erin Lynn 2011

机译：新生，成年和老年睾丸中的Leydig细胞干/前体细胞
6. Effects of Neuroendocrine CB1 Activity on Adult Leydig Cells [O] . Gilda Cobellis, Rosaria Meccariello, Rosanna Chianese, 2016

机译：神经内分泌CB1活性对成年Leydig细胞的影响
7. Effects of neuroendocrine CB1 activity on adult Leydig cells. [O] . Cobellis, G, Meccariello, R, Chianese, R, 2016

机译：神经内分泌CB1活性对成年Leydig细胞的影响。
8. Immature Rat Leydig Cells are Intrinsically Less Sensitive Than Adult LeydigCells to Ethane Dimethanesulfonate [R] . Kelce, W. R., Zirkin, B. R., Ewing, L. L. 1991

机译：未成熟的大鼠Leydig细胞本质上不如成人LeydigCells对乙烷二甲磺酸盐敏感

Effects of Neuroendocrine CB1 Activity on Adult Leydig Cells

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