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首页> 外文期刊>Gastroenterology Report >Diagnosis and management of parastomal pyoderma gangrenosum
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Diagnosis and management of parastomal pyoderma gangrenosum

机译:副细菌性坏疽性脓皮病的诊断和处理

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Parastomal pyoderma gangrenosum (PPG) is an unusual neutrophilic dermatosis characterized by painful, necrotic ulcerations occurring in the area surrounding an abdominal stoma. It typically affects young to middle-aged adults, with a slight female predominance. The underlying etiology for PPG remains enigmatic but aberrant immune response to injury may play a pivotal role. The reported risk factors for the development of PPG include the presence of extra-intestinal manifestations, autoimmune disorders and obesity, along with local factors, such as the presence of parastomal hernia or pressure ulcer. PPG can develop at any time after the stoma construction. The histopathological features of PPG are not pathognomonic and its diagnosis is mainly based on clinical features. The management of PPG often requires a multidisciplinary approach, with a combination of local wound care and systemic medications.
机译:副胃坏疽性脓皮病(PPG)是一种异常的嗜中性皮肤病,其特征是在腹部气孔周围区域发生疼痛性坏死性溃疡。它通常影响年轻到中年成年人,女性占主导地位。 PPG的潜在病因仍然是谜,但对损伤的异常免疫反应可能起关键作用。据报道,PPG发生的危险因素包括肠外表现,自身免疫性疾病和肥胖症,以及局部因素,例如副口疝或压疮等。 PPG可以在造口后的任何时间发展。 PPG的组织病理学特征不是病理学特征,其诊断主要基于临床特征。 PPG的管理通常需要采用多学科方法,并结合局部伤口护理和全身药物治疗。

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