Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia

Berlin L. Londono-Renteria; Heman Shakeri; Paula Rozo-Lopez; Michael J. Conway; Natasha Duggan; Majid Jaberi-Douraki; Tonya M. Colpitts

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Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia

机译：在哥伦比亚认识埃及伊蚊D7唾液蛋白的人抗体的血清学调查

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BackgroundDengue is one of the most geographically significant mosquito-borne viral diseases transmitted by Aedes mosquitoes. During blood feeding, mosquitoes deposit salivary proteins that induce antibody responses. These can be related to the intensity of exposure to bites. Some mosquito salivary proteins, such as D7 proteins, are known as potent allergens. The antibody response to D7 proteins can be used as a marker to evaluate the risk of exposure and disease transmission and provide critical information for understanding the dynamics of vector–host interactions.

机译：背景登革热是伊蚊传播的地理上最重要的蚊媒病毒疾病之一。在采血期间，蚊子会沉积唾液蛋白，从而诱导抗体反应。这些可能与被叮咬的强度有关。一些蚊唾液蛋白，例如D7蛋白，被称为强力过敏原。对D7蛋白的抗体反应可以用作评估暴露和疾病传播风险的标志物，并为了解载体与宿主相互作用的动力学提供关键信息。

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《Frontiers in Public Health》 |2018年第2期|共页
作者
Berlin L. Londono-Renteria; Heman Shakeri; Paula Rozo-Lopez; Michael J. Conway; Natasha Duggan; Majid Jaberi-Douraki; Tonya M. Colpitts;
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中图分类个人卫生;
关键词
Aedes salivaD7antibody levelsbiomarkerdengue;

机译：埃及伊蚊唾液D7抗体水平;

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1. Human IgG antibody response to Aedes aegypti Nterm-34 kDa salivary peptide as an indicator to identify areas at high risk for dengue transmission: A retrospective study in urban settings of Vientiane city, Lao PDR [J] . NdilleE.E., Dubot-PérèsA., DoucoureS., Tropical Medicine and International Health: TM and IH . 2014,第5期

机译：埃及伊蚊Nterm-34 kDa唾液肽的人IgG抗体反应可作为鉴定高登革热传播风险区域的指标：老挝万象市区的回顾性研究
2. First Attempt To Validate Human IgG Antibody Response to Nterm-34kDa Salivary Peptide as Biomarker for Evaluating Exposure to Aedes aegypti Bites [J] . Emmanuel Elanga Ndille, Souleymane Doucoure, Georgia Damien, PLOS Neglected Tropical Diseases . 2012,第11期

机译：首次尝试验证人IgG抗体对Nterm-34kDa唾液肽的反应，以此作为评估埃及伊蚊叮咬暴露的生物标记。
3. Association of human immune response to Aedes aegypti salivary proteins with dengue disease severity. [J] . Machain-Williams C., Mammen M. P. Jr., Zeidner N. S., Parasite Immunology . 2012,第1期

机译：人类对埃及伊蚊唾液蛋白免疫应答与登革热疾病严重程度的关系。
4. Direct MALDI analysis of naturally cleaved human saliva samples: Mapping to a series of KPQ-terminated peptides from small salivary proteins. [C] . Kenneth C. Parker, Na Tian, Frank Oppenheim, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2013

机译：直接MALDI对天然切碎的人类唾液样品的分析：测绘到来自小唾液蛋白的一系列KPQ封端的肽。
5. Identification of Culex tarsalis D7 salivary protein and role of salivary protein vaccine on subsequent West Nile virus infection [D] . Reagan, Krystle Lynn 2010

机译：tar库蚊D7唾液蛋白的鉴定及其在随后的西尼罗河病毒感染中的作用
6. Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia [O] . Berlin L. Londono-Renteria, Heman Shakeri, Paula Rozo-Lopez, 2018

机译：在哥伦比亚识别埃及伊蚊D7唾液蛋白的人抗体的血清学调查
7. Use of anti-Aedes aegypti salivary extract antibody concentration to correlate risk of vector exposure and dengue transmission risk in Colombia. [O] . Berlin Londono-Renteria, Jenny C Cardenas, Lucio D Cardenas, 2013

机译：使用抗埃及伊蚊唾液提取物抗体浓度来关联哥伦比亚的媒介暴露风险和登革热传播风险。
8. Ingestion and Development of Wuchereria bancrofti in Culex quinquefasciatus, Anopheles gambiae and Aedes aegypti after Feeding on Humans with Varying Densities of Microfilariae in Tanzania [R] . McGreevy, P. B., Kolstrup, N., Tao, J., 1982

机译：在坦桑尼亚饲养不同密度的微丝蚴的人类饲养后，在Culex quinquefasciatus，冈比亚按蚊和埃及伊蚊中摄取和开发Wuchereria bancrofti

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Serosurvey of Human Antibodies Recognizing Aedes aegypti D7 Salivary Proteins in Colombia

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