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Vaginal Microbiomes Associated With Aerobic Vaginitis and Bacterial Vaginosis

机译:阴道微生物群与有氧性阴道炎和细菌性阴道病相关

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A healthy vaginal microbiota is considered to be significant for maintaining vaginal health and preventing infections. However, certain vaginal bacterial commensal species serve an important first line of defense of the body. Any disruption of this microbial barrier might result in a number of urogenital conditions including aerobic vaginitis (AV) and bacterial vaginosis (BV). The health of the vagina is closely associated with inhabitant microbiota. Furthermore, these microbes maintain a low vaginal pH, prevent the acquisition of pathogens, stimulate or moderate the local innate immune system, and further protect against complications during pregnancies. Therefore, this review will focus on vaginal microbial “health” in the lower reproductive tract of women and on the physiological characteristics that determine the well-being of reproductive health. In addition, we explore the distinct versus shared characteristics of BV and AV, which are commonly associated with increased risk for preterm delivery.
机译:健康的阴道微生物群被认为对于维持阴道健康和预防感染很重要。但是,某些阴道细菌共生物种可为人体提供重要的第一道防线。该微生物屏障的任何破坏都可能导致许多泌尿生殖器疾病,包括需氧性阴道炎(AV)和细菌性阴道病(BV)。阴道的健康状况与居民微生物群密切相关。此外,这些微生物维持较低的阴道pH值,防止病原体的获取,刺激或调节局部先天免疫系统,并进一步防止怀孕期间的并发症。因此,本综述将重点关注女性下生殖道的阴道微生物“健康”以及决定生殖健康状况的生理特征。此外,我们还探讨了BV和AV的独特与共同特征,这些特征通常与早产风险增加有关。

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