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首页> 外文期刊>Majallah-i pizishki-i Urumiyah. >EVALUATION OF DEMOGRAPHIC CHARACTERISTICS AND RENAL FUNCTION INDICES IN ACUTE TRAMADOL INTOXICATED PATIENTS IN AYATOLLAH TALEGHANI HOSPITAL, URMIA, IRAN
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EVALUATION OF DEMOGRAPHIC CHARACTERISTICS AND RENAL FUNCTION INDICES IN ACUTE TRAMADOL INTOXICATED PATIENTS IN AYATOLLAH TALEGHANI HOSPITAL, URMIA, IRAN

机译：伊朗乌拉圭塔拉甘尼医院急性Tramadol含毒急性患者的人口统计学特征和肾功能指标评估

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Background & Aims : Since acute tramadol poisoning is related to several clinical complications. The aim of this study was to evaluate the epidemiologic, demographic and renal function indices in acute tramadol intoxicated patients. Materials & Methods : In this retrospective descriptive study, all patients admitted to Taleghani hospital of Urmia, Iran, were evaluated during a one-year period. Patients’ demographic data and the results of laboratory tests were imported to computer and analyzed. Results : From 254 tramadol intoxicated patients, 219 (86.2%) were male and 35 (13.8%) female.?The patients’ mean age was 23.29 (SD = 7.04)?years. Most patients were single (69.3%).?The ingested tramadol doses were known in 162 cases with average of 1837.35 mg (SD = 2347.36). Three patients (1.2%) had hyperkalemia, Based on laboratory and clinical findings, renal dysfunction and acute renal failure were detected in 29 and 6 patients, respectively. Four patients with acute renal failure recovered by treatment, one patient underwent hemodialysis and one patient expired despite of medical cares. Conclusion : Acute renal failure and hyperkalemia are side effects of tramadol intoxication that should be considered in diagnosis, treatment and follow-up of these patients. Our study may be a beginning for further investigations for renal complications of tramadol toxicity.
机译：背景与目的：由于急性曲马多中毒与几种临床并发症有关。这项研究的目的是评估急性曲马多中毒患者的流行病学，人口统计学和肾功能指标。材料与方法：在这项回顾性描述性研究中，对在伊朗乌尔米亚的塔莱加尼医院入院的所有患者进行了为期一年的评估。将患者的人口统计数据和实验室检查结果导入计算机并进行分析。结果：254名曲马多中毒患者中，男性219名（86.2％），女性35名（13.8％）。患者的平均年龄为23.29岁（标准差= 7.04）岁。大多数患者是单身的（69.3％）。162例已知曲马多的摄入剂量为平均1833.75 mg（SD = 2347.36）。 3名患者（1.2％）有高钾血症，根据实验室和临床发现，分别在29名和6名患者中发现了肾功能不全和急性肾衰竭。尽管有医疗护理，但有4例急性肾衰竭患者通过治疗得以康复，1例患者接受了血液透析，1例患者死亡。结论：急性肾功能衰竭和高钾血症是曲马多中毒的副作用，在这些患者的诊断，治疗和随访中应予以考虑。我们的研究可能是进一步研究曲马多毒性肾脏并发症的开始。

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