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Applications of proteomics in marine ecology

机译:蛋白质组学在海洋生态学中的应用

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ABSTRACT: Proteomics emerged in the beginning of the 1990s due to the need for new methods for protein analysis. Proteomics is a much newer discipline than genomics, and confronts similar challenges to those that genomics researchers faced in the implementation of large-scale sequencing programs. The definition of proteomics as the use of quantitative protein-level measurements of gene expression to characterize biological processes and decipher the mechanisms of gene expression control fits in with any biological approach. In the present study, proteomics is discussed and defined in parallel with genomics, given that many authors integrate proteomics in the context of functional genomics. In this Theme Section, several facets of proteomics in marine ecology were adressed: capacity, or what can be done, utility, the technology possibilities, and how to use the data obtained. As with any new and interesting technology, the expectations often exceed reality. The applications of proteomics, the advantages and disadvantages, as well as a few limitations are discussed.
机译:摘要:由于需要新的蛋白质分析方法,蛋白质组学在1990年代初出现。蛋白质组学是一门比基因组学新的学科,它面临着与基因组学研究人员在实施大规模测序程序中所面临的挑战相似的挑战。蛋白质组学的定义是使用定量的蛋白质表达水平的基因表达测量来表征生物学过程并破译基因表达控制机制,这与任何生物学方法都相吻合。在本研究中,鉴于许多作者在功能基因组学的背景下整合了蛋白质组学,因此与蛋白质组学同时讨论和定义了蛋白质组学。在本主题部分中,探讨了蛋白质组学在海洋生态学中的几个方面:容量或可以做什么,实用性,技术可能性以及如何使用获得的数据。与任何新的有趣技术一样,期望值通常超过现实。讨论了蛋白质组学的应用,优缺点和一些局限性。

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