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首页> 外文期刊>Marmara Medical Journal >VALUATION OF TREATMENT RESULTS OF PATIENTS TREATED WITH SPLENECTOMY FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA
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VALUATION OF TREATMENT RESULTS OF PATIENTS TREATED WITH SPLENECTOMY FOR IDIOPATHIC THROMBOCYTOPENIC PURPURA

机译：特发性全血栓性胸膜积水患者全科治疗的治疗效果评估

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Purpos: The treatment results of patients treated with splenectomy for idiopathic thrombocytopenic purpura were evaluated in this study. Patients and Methods: Patients treated with splenectomy for idiopathic trombocytopenic purpura between 1999-2006 were retrospectively evaluated. Patients’ age, gender, preoperative and postoperative medical treatments, duration from the beginning of the treatment to surgery, vaccination status, type of surgical treatment, presence of accessory spleen, and postoperative complications were recorded and early and late postoperative trombocyte responses were evaluated. Results: Five male and eight female patients with a mean age of 38 (14-67) were included in the study. Bleeding was the presenting sign in all patients. Splenectomy was performed since two patients were dependent on and 11 patients were unresponsive to steroid treatment. Two patients had temporary bleeding and hematoma whereas two patients had pneumonia as postoperative complications. Eleven patients (84%) had complete response, one patient (8%) had partial response and one patient (8%) was unresponsive in early postoperative follow-up period. During long-term follow-up, nine patients (69%) had complete response, one patient (8%) had partial response and three patients (23%) were unresponsive to splenectomy. Conclusion: Splenectomy can be performed safely in idiopathic trombocytopenic purpura patients unresponsive to medical treatment to obtain sustained response.
机译：目的：本研究评估了脾切除术治疗特发性血小板减少性紫癜的患者的治疗结果。患者和方法：回顾性分析1999-2006年因脾切除术治疗的特发性血小板减少性紫癜的患者。记录患者的年龄，性别，术前和术后药物治疗，从治疗开始到手术的持续时间，疫苗接种状况，外科治疗的类型，辅助脾的存在以及术后并发症的发生，并评估术后早期和晚期淋巴细胞的反应。结果：五名男性和八名女性患者，平均年龄在38岁（14-67岁）。所有患者均出现出血迹象。进行脾切除术是因为有2例患者依赖和11例患者对类固醇治疗无反应。两名患者出现暂时性出血和血肿，而两名患者则患有肺炎作为术后并发症。在术后早期随访期间，11例患者（84％）完全缓解，1例患者（8％）部分缓解，1例患者（8％）无缓解。在长期随访中，9例患者（69％）完全缓解，1例患者（8％）部分缓解，3例患者（23％）对脾切除术无反应。结论：对药物治疗无反应的特发性血小板减少性紫癜患者可以安全地行脾切除术，以获得持续的反应。

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