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首页> 外文期刊>Medical Journal of Shree Birendra Hospital >Association of Helicobacter Pylori Infection and Stomach Cancer
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Association of Helicobacter Pylori Infection and Stomach Cancer

机译：幽门螺杆菌感染与胃癌的关系

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Introduction: Helicobacter pylori (H. Pylori) as a primary etiological factor in carcinoma stomach. Associationof H. Pylori in gastric cancer has been documented to be in more than 50% of cases. In underdevelopedcountries, this association is shown to be much higher according to different studies.Methods: A prospective observational study of 40 consecutive cases of carcinoma stomach was under takenin surgical department of Shree Birendra hospital and Bir hospital, for a period of two years 2009 to 2011.Location and pathological types of the lesion were noted and all specimens were investigated to see presenceof helicobacter pylori by rapid urease test (RUT) and histological examination.Results: Out of 40 patients, helicobacter pylori positivity was seen in 27 (67.5%) cases by both rapid ureasetest and Histopathological examination (HPE). Regarding the pathological types, out of 26 intestinal type of castomach, 20 (76.92%) cases were positive for H. pylori infection, whereas out of 14 diffuse type of ca stomach,7(50%) cases were positive for H. pylori. In 29 cases of distal ca stomach, H. pylori positivity was seen in 22(75.86%) cases, whereas in rest of the 11 cases the lesion involved other part of the stomach, H. pylori positivitywas seen in 5(45.45%) cases.Conclusion: Helicobacter pylori infection is higher in prevalence in cases of stomach cancer. Its associationwith intestinal histological type of stomach cancer is more common than diffuse type. There is higher prevalenceof Helicobacter pylori infection in distal carcinoma. doi: http://dx.doi.org/10.3126/mjsbh.v12i2.12927
机译：简介：幽门螺杆菌（H. Pylori）是胃癌的主要病因。幽门螺杆菌与胃癌的关联已被证明在50％以上的病例中。方法：在Shree Birendra医院和Bir医院的外科部门进行的一项连续40例胃癌病例的前瞻性观察研究在2009年至2009年之间进行，为期两年。 2011年。记录病灶的位置和病理类型，并通过快速尿素酶试验（RUT）和组织学检查对所有标本进行检查，以查看是否存在幽门螺杆菌。结果：40例患者中，幽门螺杆菌阳性率为27例（67.5％）。快速尿素定型和组织病理学检查（HPE）的病例。就病理类型而言，在26种肠型的卡氏肉中，幽门螺杆菌感染为20例（76.92％），而在14种弥散型胃癌中幽门螺杆菌为阳性。在29例远端胃癌中，幽门螺杆菌阳性为22例（占75.86％），而在11例中，其余部分累及胃的其他部位，幽门螺杆菌阳性为5例（占45.45％）。结论：胃癌患者的幽门螺杆菌感染率较高。它与胃癌的肠组织学类型的关系比弥漫型更为常见。远端癌中幽门螺杆菌感染的发生率较高。 doi：http：//dx.doi.org/10.3126/mjsbh.v12i2.12927

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