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Comparative analysis of effectiveness of treatment with anti-TB drugs of the 1st and 2nd lines for children and adolescents with multidrug resistant tuberculosis

机译:一线和二线抗结核药物治疗儿童和青少年多药耐药性肺结核的疗效比较分析

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The paper shows results of study on comparative treatment effectiveness in children and adolescents with from multi drug resistant tuberculosis MDR TB (2000-2008) treated with anti-TB drugs of the 2nd line (80 patients) and 1st line (80 patients) in the Kazakhstan. It was stated in patients with MDR TB that outcomes of treatment were successful in 91.2%, but relapse development of TB disease occurred in 12.7% of cases, and 5 (6.2%) patients died (P ≤0.05). Thus, patients with MDR TB need to be treated with anti-TB drugs of the 2nd line accordingly to their DST.
机译:本文显示了在第二线(80例)和第一线(80例)的抗结核药物治疗的多药耐药结核MDR TB(2000-2008)儿童和青少年中比较治疗效果的研究结果。哈萨克斯坦。据说在耐多药结核病患者中,治疗结果成功率为91.2%,但结核病复发发生率为12.7%,死亡5例(6.2%)(P≤0.05)。因此,耐多药结核病患者需要根据其DST接受第二线抗结核药物治疗。

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