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首页> 外文期刊>Medical science monitor : >Familial occurrence of hemangioblastoma of the central nervous system. A report of three cases
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Familial occurrence of hemangioblastoma of the central nervous system. A report of three cases

机译：家族性中枢神经系统血管母细胞瘤的发生。一篇三个案例的报告

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The occurrence of hemangioblastoma in three brothers is reported. All of them developed posterior fossa tumors and one additionally developed a spinal tumor in the thoracic region. The clinical symptoms and signs manifested themselves in the early twenties in all three cases. None of the brothers demonstrated angiomatosis of the retina and only in one was mild erythrocytosis detected. Surgical removal was carried out in two patients and in one was limited only to a ventricular tap. In the remaining brother excision was followed by radiotherapy. Diagnosis was established on the basis of histologic examination in of the literature has shown that only in a few reports has the diagnosis been confirmed histologically in all presented cases. The importance of screening all the members of families in cases of suspected or diagnosed hemangioblastoma is emphasized.
机译：据报道三兄弟中血管母细胞瘤的发生。他们都发展为后颅窝肿瘤，另外一个在胸腔区域发展为脊柱肿瘤。在这三例病例中，临床症状和体征均在二十年代初表现出来。兄弟俩均未表现出视网膜血管瘤病，只有一个发现轻度红细胞增多症。两名患者进行了手术切除，其中一名仅限于心室抽头。在剩下的兄弟中，切除后进行放射治疗。在组织学检查的基础上建立的诊断表明，只有少数报告对所有病例进行了组织学确认。强调了在怀疑或诊断成血管母细胞瘤的情况下筛查所有家庭成员的重要性。

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