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Treatment of community-acquired pneumonia: a descriptive study in an Apulian department of internal medicine.

机译：社区获得性肺炎的治疗：阿普利亚内科的一项描述性研究。

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Background: Infections of the lower airways pose a serious problem forthe health service, both because of the burden of the disease and because of the large number of resourcesthat need to be devoted to treating it. Material/Methods: The present study describes the use of antibioticsto treat acute bronchopneumonia in the Internal Medicine Department "Cesare Frugoni" of a universityhospital in southern Italy. A total of 493 patients were studied during a 4.5-year period. Results: In98.2% of cases an empirical approach to treatment was adopted, and only in 57 patients was targeted treatmentadministered. Mean duration of the antibiotic therapy was 11.3 days, with a wide range. Assessment ofprognosis in the different groups showed that this did not seem to depend on the type of treatment approachor on the type and/or number of antibiotics used. Instead, targeted therapy was correlated with a shorterduration of treatment. Blood culture was very rarely carried out. The almost invariably empirical approachto treatment of bronchopneumonia infections resulted in longer hospital stay and a greater consumptionof antibiotics, often of latest generation. Conclusions: Therefore, more studies would be useful to investigatethe real adherence to the guidelines in the clinical practice. Finally, blood culture should be performedroutinely in these patients, although the time required for the test could be a limiting factor.
机译：背景：下呼吸道的感染给卫生服务带来了严重的问题，这既是由于疾病负担，又是因为需要投入大量资源来治疗这种疾病。材料/方法：本研究描述了在意大利南部大学医院内科“切萨雷·弗鲁戈尼”（Cesare Frugoni）中使用抗生素治疗急性支气管肺炎的方法。在4.5年的时间里共研究了493例患者。结果：在98.2％的病例中，采用了经验疗法，只有57例患者接受了靶向治疗。抗生素治疗的平均持续时间为11.3天，范围广泛。对不同组的预后评估表明，这似乎并不取决于治疗方法的类型或所用抗生素的类型和/或数量。相反，靶向治疗与较短的治疗时间相关。很少进行血液培养。治疗支气管肺炎感染的几乎总是经验性的方法导致住院时间更长，并且抗生素的消耗量更大，这通常是最新一代的。结论：因此，更多的研究将有助于研究临床实践中对指南的真正遵守情况。最后，这些患者应常规进行血液培养，尽管测试所需的时间可能是限制因素。

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