...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Medical science monitor : >Comparison of pulsatile and non-pulsatile cardiopulmonary bypass in patients with chronic obstructive pulmonary disease
【24h】

Comparison of pulsatile and non-pulsatile cardiopulmonary bypass in patients with chronic obstructive pulmonary disease

机译：慢性阻塞性肺疾病患者搏动性和非搏动性体外循环的比较

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background:Patients with chronic obstructive pulmonary disease have an increased risk of mortality and morbidity after open-heart surgery. This is mostly due to a dysfunction of the pulmonary system during and after non-pulsatile cardiopulmonary bypass. The purpose of this study was to compare the pulsatile and non-pulsatile blood flows during cardiopulmonary bypass in patients with chronic obstructive pulmonary disease.Material/Methods:This is a prospective study. Ten patients with chronic obstructive pulmonary disease had open-heart surgery with pulsatile flow, and another 9 patients with non-pulsatile flow. We compared clinical, hemodynamic, biochemical and hematological parameters and arterial and venous blood gases before initiating cardiopulmonary bypass, at aortic cross-clamping and de-clamping, and 1 and 24 hours postoperative.Results:In the pulsatile flow group, systemic vascular resistance at the time of aortic cross clamping (p=0.041), pulmonary vascular resistance 1 hour postoperative (p=0.05), and the percentage of neutrophils 1 hour postoperative (p=0.034) were significantly lower than those of the non-pulsatile group. Though white blood cell count was significantly high in the pulsatile group 1 hour postoperative, absolute neutrophil count was significantly low (p=0.034). The postoperative mechanical ventilation period was significantly shorter in the pulsatile flow group (p=0.016).Conclusions:Pulsatile blood flow during cardiopulmonary bypass has a favorable influence on patients with chronic obstructive pulmonary disease, who have high risk in open-heart surgery.
机译：背景：患有慢性阻塞性肺疾病的患者在进行心脏直视手术后死亡和发病的风险增加。这主要归因于非搏动性心肺旁路手术期间和之后的肺系统功能障碍。这项研究的目的是比较慢性阻塞性肺疾病患者在体外循环期间的搏动和非搏动血流。材料/方法：这是一项前瞻性研究。患有慢性阻塞性肺疾病的10例患者接受了搏动性心脏直视手术，另外9例非搏动性血液患者。我们比较了开始心肺旁路手术前，主动脉钳夹和去钳夹以及术后1和24小时的临床，血液动力学，生化和血液学参数以及动脉和静脉血气的结果。结果：在脉动血流组，全身血管阻力为术后1小时主动脉夹钳时间（p = 0.041），肺血管阻力（p = 0.05）和术后1小时中性粒细胞百分比（p = 0.034）均显着低于非搏动组。尽管搏动组术后1小时白细胞计数显着较高，但绝对中性粒细胞计数却显着较低（p = 0.034）。结论：体外循环期间的多动血流对慢性心梗性肺部疾病患者有良好的影响，这些患者有开胸手术的高风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号