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The role of neuroimaging in the investigation of patients with single seizures, febrile seizures, or refractory partial seizures

机译:神经影像学在单发性癫痫,高热性癫痫或难治性部分性癫痫患者调查中的作用

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Seizures are a symptom of an underlying brain disorder. The accurate identification of the nature of the disease generating the seizures facilitates treatment and can prevent further brain damage. The understanding of the physiopathology underlying the seizures has been greatly enhanced by the possibility to examine these patients with advanced forms of neuroimaging. Among different forms of investigation, neuroimaging techniques play a major role in diagnosis and decision-making in the care of patients with epilepsy. We review the contributions of current methods of imaging in the investigation of patients with single seizures, febrile seizures or refractory seizures, assessing the practical aspects, benefits, and operational costs of various neuroimaging techniques. The focus is on MRI, which is the imaging modality of choice for outpatient investigation. We also assessed the benefits from CT scans, which remain the first option for emergency seizure assessment. The aim was to evaluate how the structural, functional and metabolic information provided by modern techniques of neuroimaging decreases the need for additional investigation and speeds the management of these epileptic disorders. This makes it possible to accurately define the location and the nature of the epileptogenic lesions related to seizures.
机译:癫痫发作是潜在脑部疾病的症状。准确识别引起癫痫发作的疾病的性质有助于治疗,并可以防止进一步的脑损伤。通过对这些患者进行神经影像学检查的可能性,极大地增强了对癫痫发作的生理病理学的理解。在不同的调查形式中,神经影像技术在癫痫患者的护理诊断和决策中起着重要作用。我们回顾了当前的成像方法在单发性癫痫,高热性癫痫或难治性癫痫患者的调查中的贡献,评估了各种神经成像技术的实用性,益处和运营成本。重点是MRI,这是门诊检查的首选成像方式。我们还评估了CT扫描的好处,CT扫描仍然是紧急癫痫评估的首选。目的是评估现代影像学技术提供的结构,功能和代谢信息如何减少对其他研究的需求,并加快这些癫痫病的治疗速度。这使得可以准确定义与癫痫发作有关的癫痫病灶的位置和性质。

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