...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Medical science monitor : >Analysis of distant sequelae of congenital toxoplasmosis in children and adults
【24h】

Analysis of distant sequelae of congenital toxoplasmosis in children and adults

机译：儿童和成人先天性弓形虫病远距离后遗症分析

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The study aimed at presenting distant sequelae of congenital toxoplasmosis in 15 children and in 5 adults who were not treated in the course of the first year of life. The retrospective analysis as well as a set of supplementary studies (neurologic, ophthalmologic studies, computerised tomography of the head (CT), serological examination using ELISA test (Vidas, bio Merieux)) were performed to demonstrate IgM and IgG antibodies against T. gondii antigen. Type of neurological disturbances varied and ranged between 5.0% do 50.0% of cases. CT lesions included widening of lateral ventricles (30.0%), their asymmetry (35.0%), intracranial calcifications (65.0%) located mainly in lateral ventricles and in both hemispheres (35.0%). Lesions in the organs of sight included mainly amblyopia due to diffuse chorioretinal scars (70.0%), located mainly within retinal macula (50.0%). In all the patients, IgG antibodies were present (ELISA, DA), but in children they reached high titres and in two of them they were accompanied by IgM antibodies because of reactivation of the pathological process. The complex studies performed in the observed 20 patients proved that clinical pathology in the form of CNS lesions (85.0%) and lesions in the organs of sight (80.0%) represent late sequelae of congenital toxoplasmosis in patients who remained undiagnosed and were not treated in the first year of life.
机译：这项研究的目的是在15岁的儿童和5名成人的第一年中，没有出现先天性弓形虫病的后遗症。进行了回顾性分析以及一系列补充研究（神经，眼科研究，头部计算机断层扫描（CT），使用ELISA测试的血清学检查（Vidas，bio Merieux）），以证明针对弓形虫的IgM和IgG抗体。抗原。神经系统疾病的类型各不相同，介于5.0％和50.0％之间。 CT病变包括侧脑室增宽（30.0％），不对称性（35.0％），颅内钙化（65.0％），主要位于侧脑室和两个半球（35.0％）。视器官中的病变主要是由于弥漫性脉络膜视网膜瘢痕引起的弱视（70.0％），主要位于视网膜黄斑内（50.0％）。在所有患者中，均存在IgG抗体（ELISA，DA），但在儿童中，它们的滴度很高，在其中两个患者中，由于病理过程的重新激活，它们都伴有IgM抗体。在观察到的20名患者中进行的复杂研究证明，中枢神经系统病变（85.0％）和视器官病变（80.0％）形式的临床病理表现为先天性弓形虫病的晚期后遗症，这些患者仍未被诊断并未经治疗。人生的第一年。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号