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Detection of cardiac changes in juvenile rheumatoid arthritis by non-invasive methods of circulatory system investigation

机译:通过非侵入性循环系统研究方法检测青少年类风湿性关节炎的心脏变化

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The aim of the study was a complex evaluation of circulatory system in children with juvenile rheumatoid arthritis (j.r.a.) on the basis of available non-invasive methods of circulatory system investigation. 89 children with j.r.a. were examined. Obtained results were compared with the results recorded in 50 healthy children of corresponding age group and gender. Anamnesis, physical and radiological examinations revealed low percentage of changes. Patients with generalised j.r.a. more often displayed tachycardia and low heart sounds, in single cases pericardial friction murmur was detected. Changes in ECG were observed in approx. 40% patients, and they frequently concerned ST segment and T wave and were diagnosed in children with generalised form of the disease. Deviations in echocardiography were observed in over 60% cases. Statistically significant decrease of left ventricular ejection fraction (%EF) and percentage shortening fraction of left ventricle (%SF) were recorded in generalised j.r.a. when compared with other forms of the disease and control group. There was a statistically significant difference in the decrease of intraventricular septum - systole (IVSs%) in generalised and polyarticular j.r.a. when related to oligoarticular form of the disease. Reduced left ventricular posterior wall - systole (%LVPWs) was only observed in patients with generalised and oligoarticular j.r.a. Pericardial pathology was detected in 1/3 investigations, most often in generalised j.r.a. It was manifested by pericardial exudate or excessive pericardial saturation. We analysed the presence of changes in echo and ECG with respect to disease duration. It was found that changes in ECG and echo were significantly more frequent during the first 5 years of j.r.a. when compared with later phase of the disease.
机译:该研究的目的是在可利用的非侵入性循环系统研究方法的基础上,对青少年类风湿性关节炎(j.r.a.)患儿的循环系统进行综合评估。 89名儿童被检查。将获得的结果与在相应年龄组和性别的50名健康儿童中记录的结果进行比较。回忆,身体和放射学检查发现变化的百分比较低。全身性j.r.a.更常显示心动过速和低心音,在单例情况下,可检测到心包摩擦杂音。观察到心电图的变化。 40%的患者,他们经常关注ST段和T波,并被诊断出患有该病的广义患儿。超过60%的病例观察到超声心动图的偏差。广义j.r.a.记录了左心室射血分数(%EF)和左心室缩短百分比(%SF)的统计显着下降。与其他形式的疾病和对照组相比。全身性和多关节性j.r.a的室间隔-收缩期(IVSs%)的减少在统计学上有显着差异。与疾病的少关节形式有关时。仅在全身性和少关节型j.r.a.患者中观察到左心室后壁-收缩期减少(%LVPWs)。在1/3的研究中发现了心包病理,最常见的是在一般性的j.r.a.心包渗出液或过度的心包饱和度表现出来。我们分析了回声和心电图关于疾病持续时间的变化。发现在J.r.a.的头5年中,心电图和回声的变化明显更为频繁。与疾病的后期比较。

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