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首页> 外文期刊>Medicine. >Association of smoking with risk of stroke in middle-aged and older Chinese: Evidence from the China National Stroke Prevention Project
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Association of smoking with risk of stroke in middle-aged and older Chinese: Evidence from the China National Stroke Prevention Project

机译：中老年人吸烟与中风风险的关联：来自中国预防中风项目的证据

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Although the impacts of smoking on health are well established, it is unclear on how they affect the Chinese population aged ≥40 years. This study aimed to investigate the association between smoking and risk of stroke in middle-aged and older Chinese adults, based on the data from the China National Stroke Prevention Project. A community-based cross-sectional study with 12,704 (5681 men, 7023 women) Chinese adults aged ≥40 years was conducted to examine the association of smoking with stroke . Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs). Among the study population, a total of 524 stroke survivors were identified. The age-adjusted prevalence of stroke was 4.06% for both sexes, 2.95% for women, and 5.38% for men. The multivariate-adjusted ORs (95% CI) of stroke associated with current cigarette smoking and former cigarette smoking were 1.67 (1.24–2.25) and 1.93 (1.29–2.87), respectively. Compared with those who were never-smokers, the multivariate-adjusted OR of stroke (95% CI) were 1.48 (0.96 to –2.29), 1.75 (1.20–2.56), and 2.37 (1.20 to –4.68) for those who smoked 1 to 10, 11 to 20, and ≥21 cigarettes per day; and 0.51 (0.19 to –1.42), 1.90 (1.36 to –2.67), and 2.01 (1.17 to –3.46) for those who smoked 1 to 19, 20 to 39, and ≥40 years, respectively (both P 60 years old, or without family history of stroke than their counterparts. This study suggests the increased odds of stroke in current cigarette smokers with a graded increase in prevalent risk that depended on how many cigarettes and how many years were smoked. Moreover, quitting smoking appears to decrease this excess risk substantially.
机译：尽管吸烟对健康的影响是众所周知的，但尚不清楚吸烟如何影响≥40岁的中国人口。这项研究的目的是根据中国预防中风项目的数据，调查中国中老年人吸烟与中风风险之间的关系。一项基于社区的横断面研究对12岁以上40岁以上的中国成年人进行了研究，调查了12704名（5681名男性，7023名女性）吸烟与中风的关系。多变量逻辑回归用于计算比值比（OR）和95％置信区间（CIs）。在研究人群中，总共鉴定出524名中风幸存者。年龄调整后的中风患病率，男女均为4.06％，女性为2.95％，男性为5.38％。与当前吸烟和以前吸烟相关的中风的多元校正OR（95％CI）分别为1.67（1.24–2.25）和1.93（1.29–2.87）。与不吸烟者相比，吸烟者的中风多元校正后OR（95％CI）为1.48（0.96至–2.29），1.75（1.20–2.56）和2.37（1.20至–4.68）每天10到11到20支和≥21支香烟;吸烟年龄分别为1至19岁，20至39岁和40岁以上（均为P 60岁）的人分别为0.51（0.19至–1.42），1.90（1.36至–2.67）和2.01（1.17至–3.46）。这项研究表明，当前卷烟吸烟者的中风几率增加，流行风险的分级升高取决于卷烟的数量和吸烟年数。大大增加了风险。

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