...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Molecular and Cellular Pharmacology >Stereotactic Ablative Radiotherapy (SABR): Impact on the Immune System and Potential for Future Therapeutic Modulation
【24h】

Stereotactic Ablative Radiotherapy (SABR): Impact on the Immune System and Potential for Future Therapeutic Modulation

机译：立体定向消融放疗（SABR）：对免疫系统的影响以及未来治疗调节的潜力

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Sh Faisal 14.00 Sh Faisal 14.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Sh Faisal 14.00 Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;} Stereotactic ablative radiotherapy (SABR) has been demonstrated to provide excellent local control in several malignancies. Recent reports have suggested that this ablative dose may impact disease outside of the radiated area. Furthermore, these studies have implicated immune modulation as the primary mechanism of disease response outside the irradiated area. More specifically, T-cell stimulation and tumor necrosis factor-alpha modulation following high dose irradiation have been suggested as the responsible components of this phenomenon. In addition, the “abscopal effect” may play a role in disease response outside of the radiated area. We review the current literature regarding the effects of ablative radiation therapy, the potential for immune modulation from it, and the mechanisms of the distant effects it elicits. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:12.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin;}
机译：Sh Faisal 14.00 Sh Faisal 14.00正常0否否否EN-US X-NONE X-NONE / *样式定义* / table.MsoNormalTable {mso-style-name：“ Table Normal”; mso-tstyle-rowband-size：0; mso-tstyle-colband-size：0; mso-style-noshow：是; mso-style-priority：99; mso-style-parent：“”; mso-padding-alt：0in 5.4pt 0in 5.4pt; mso-para-margin：0in; mso-para-margin-bottom：.0001pt; mso分页：寡妇孤儿;字体大小：12.0pt;字体家族：“ Calibri”，“ sans-serif”; mso-ascii-font-family：Calibri; mso-ascii-theme-font：minor-latin; mso-hansi-font-family：Calibri; mso-hansi-theme-font：minor-latin;} Sh Faisal 14.00正常0假否假EN-US X-NONE X-NONE / *样式定义* / table.MsoNormalTable {mso-style-name：“ Table Normal” ; mso-tstyle-rowband-size：0; mso-tstyle-colband-size：0; mso-style-noshow：是; mso-style-priority：99; mso-style-parent：“”; mso-padding-alt：0in 5.4pt 0in 5.4pt; mso-para-margin：0in; mso-para-margin-bottom：.0001pt; mso分页：寡妇孤儿;字体大小：12.0pt;字体家族：“ Calibri”，“ sans-serif”; mso-ascii-font-family：Calibri; mso-ascii-theme-font：minor-latin; mso-hansi-font-family：Calibri; mso-hansi-theme-font：minor-latin;}立体定向消融放疗（SABR）已被证明可在多种恶性肿瘤中提供出色的局部控制。最近的报告表明，这种消融剂量可能会影响辐射区域以外的疾病。此外，这些研究表明免疫调节是受辐照区域外疾病反应的主要机制。更具体地，已经提出高剂量照射后的T细胞刺激和肿瘤坏死因子-α调节是该现象的负责成分。另外，“绝对效应”可能在辐射区域之外的疾病反应中起作用。我们回顾了有关消融放射疗法的效果，从中进行免疫调节的潜力及其引起的远距离作用机理的最新文献。正常0否否否EN-US X-NONE X-NONE / *样式定义* / table.MsoNormalTable {mso-style-name：“ Table Normal”; mso-tstyle-rowband-size：0; mso-tstyle-colband-size：0; mso-style-noshow：是; mso-style-priority：99; mso-style-parent：“”; mso-padding-alt：0in 5.4pt 0in 5.4pt; mso-para-margin：0in; mso-para-margin-bottom：.0001pt; mso分页：寡妇孤儿;字体大小：12.0pt;字体家族：“ Calibri”，“ sans-serif”; mso-ascii-font-family：Calibri; mso-ascii-theme-font：minor-latin; mso-hansi-font-family：Calibri; mso-hansi-theme-font：minor-latin;}

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号