FDA Approves New Combination Treatment for Acute Myeloid Leukemia

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FDA Approves New Combination Treatment for Acute Myeloid Leukemia

机译：FDA批准用于急性髓细胞白血病的新的联合治疗

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The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3, in combination with chemotherapy. The drug is approved for use with a companion diagnostic, the LeukoStrat CDx FLT3 Mutation Assay, which is used to detect the FLT3 mutation in patients with....

机译：美国食品药品监督管理局今天批准将Rydapt（midostaurin）用于治疗患有新诊断的急性髓性白血病（AML）的成年患者，这些患者具有称为FLT3的特定基因突变，并联合化疗。该药物被批准与伴发性诊断试剂LeukoStrat CDx FLT3突变测定法一起使用，可用于检测患有...的患者的FLT3突变。

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《Molecular and Cellular Pharmacology》 |2017年第1期|共2页
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3. Comparative Effectiveness of Combination Glasdegib plus Low-Dose Cytarabine (GLAS plus LDAC) Vs Combination Venetoclax plus Low-Dose Cytarabine (VEN plus LDAC) Among Older Acute Myeloid Leukemia (AML) Patients Ineligible for Intensive Chemotherapy (NIC): Indirect Treatment Comparison (ITC) Methods [J] . Westley Tracy, Forsythe Anna, Bell Timothy J., Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

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5. Loss of Egr1 plays a role in murine leukemogenesis and may play a role in the development of acute myeloid leukemia and therapy-related acute myeloid leukemia. [D] . Joslin, John M. 2006

机译：Egr1的丢失在小鼠白血病的发生中起作用，并且可能在急性髓细胞性白血病和与治疗有关的急性髓细胞性白血病的发展中起作用。
6. The Combination Of Splanchnic Vasoconstrictors And Endoscopic Band Ligation Is An Effective Treatment Strategy For Acute Variceal Hemorrhage; But How Do We Get Those Drugs Approved By The FDA? [O] . Brett E. Fortune, Roberto Groszmann -1

机译：内脏血管收缩和内镜带结扎术相结合是急性静脉曲张破裂出血的有效治疗策略。但是我们如何获得FDA批准的那些药物？
7. Combination of splanchnic vasoconstrictors and endoscopic band ligation is an effective treatment strategy for acute variceal hemorrhage; but how do we get those drugs approved by the FDA? [O] . Brett E. Fortune, Roberto J. Groszmann 2014

机译：Splanchnic血管收缩仪和内窥镜频段连接的组合是急性变质出血的有效治疗策略;但我们如何获得由FDA批准的药物？

FDA Approves New Combination Treatment for Acute Myeloid Leukemia

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