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首页> 外文期刊>Korean Circulation Journal >Study of Compliance to Antihypertensive Medication in Korean Hypertensive Patients Using Medication Event Monitoring System
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Study of Compliance to Antihypertensive Medication in Korean Hypertensive Patients Using Medication Event Monitoring System

机译：用药物事件监测系统研究韩国高血压患者对降压药物的依从性

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BACKGROUND AND OBJECTIVES: Compliance to a prescribed antihypertensive regimen influences the management of hypertension in various steps, but studies on this issue are very rare in Korea. The medication event monitoring system (MEMS) is the gold standard in measurement of compliance, which is a special pill container, designed to electronically monitor drug intake patterns. Here, the authors investigated the compliance to the antihypertensive regimen in the cardiology practice of a tertiary care hospital using the MEMS. SUBJECTS AND METHODS: Monitoring using the MEMS was performed in 80 hypertensive patients during monotherapy. Demographic, clinical and psychological profiles were collected through a standardized questionnaire. The parameters used for compliance were the percentage of doses taken (PDT) and the percentage of doses taken correctly (PDTc), according to the prescribed regimen. RESULTS: The mean age of the patients and duration of monitoring were 53±10 years and 60±26 days, respectively. The median and range for the PDT and PDTc were 97% (88-100%) and 92% (80-97%), respectively. About 16% of patients showed relatively poor compliance (PDT CONCLUSION: Although average compliance to the single drug antihypertensive regimen was relatively high in the cardiology practice of the tertiary care hospital in this study, a significant proportion of patients show low compliance. Special consideration should be given to patients with factors predictive of poor compliance. Investigation of compliances in other clinical settings is also warranted.
机译：背景与目的：遵从规定的降压方案会在各个步骤影响高血压的治疗，但是在韩国，对此问题的研究很少。药物事件监测系统（MEMS）是合规性测量的金标准，这是一种特殊的药丸容器，旨在以电子方式监测药物摄入模式。在这里，作者研究了使用MEMS的三级医疗医院心脏病实践中对降压方案的依从性。研究对象和方法：在单药治疗期间，对80位高血压患者进行了MEMS监测。人口统计学，临床和心理概况是通过标准化问卷收集的。根据处方方案，用于依从性的参数是服用剂量的百分比（PDT）和正确服用的剂量的百分比（PDTc）。结果：患者的平均年龄和监测时间分别为53±10岁和60±26天。 PDT和PDTc的中位数和范围分别为97％（88-100％）和92％（80-97％）。大约16％的患者表现出相对较差的依从性（PDT结论：尽管在该研究中，三级医院的心脏病学实践中对单一药物降压方案的平均依从性相对较高，但仍有相当一部分患者表现出较低的依从性。应特别考虑应当给那些预测依从性差的因素的患者使用，也有必要在其他临床环境中对依从性进行调查。

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