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首页> 外文期刊>Khyber Medical University Journal >EFFECT OF PREOPERATIVE BUPIVACAINE INFILTRATION OF NEPHROSTOMY TRACT ON POST-OPERATIVE PAIN IN PATIENTS UNDERGOING PERCUTANEOUS NEPHROLITHOTOMY: A RANDOMIZED CONTROLLED TRIAL
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EFFECT OF PREOPERATIVE BUPIVACAINE INFILTRATION OF NEPHROSTOMY TRACT ON POST-OPERATIVE PAIN IN PATIENTS UNDERGOING PERCUTANEOUS NEPHROLITHOTOMY: A RANDOMIZED CONTROLLED TRIAL

机译：经皮肾上腺全切术患者术前布比卡因渗透性肾病对术后疼痛的影响：随机对照试验

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OBJECTIVES: To see the effect of bupivacaine infiltration of nephrostomytract in reducing the postoperative pain and analgesic requirements inpatients undergoing percutaneous nephrolithotomy.METHODOLOGY: This randomized controlled study was conductedat institute of kidney diseases Hayatabad Medical Complex, Peshawar,Pakistan, from June 1, 2011 to May 31, 2012. Total 66 patients (33 patientsin each group) were included in the study through consecutivenon-probability sampling technique and were randomly divided intogroup A (bupivacaine, 33 patients) and group B (placebo, 33 patients).RESULTS: Mean age was 32.2+2.7 & 31.09+2.6 years in group A & Brespectively. The mean duration of the procedure was 70.66±7.41 &72.12±.65 minutes for group A & B respectively. The overall averagepain score for group A was 4.15±1.48 on visual analogue scale, whilethat for group B was 6.06±1.02 (p 0.05). The average pain score forfemale patient was 4.07, (range 2-7) & 6.13 (range 4-8) in group A & Brespectively. The average pain score for male patient was 4.12 (range2-7) & 6.0 (range 4-7) in group A & B respectively. The effect of ageon pain perception was not significant in this study as we included onlyadult patients (≥14 years of age) and mixed response was observed inboth groups patients of different age groups.CONCLUSION: Preoperative bupivacaine infiltration of the nephrostomytract is safe and an effective way of reducing the postoperative painand analgesic requirements avoiding the adverse effects of the opioidsor non-opioids analgesics.
机译：目的：观察布比卡因渗入肾造瘘术对减少经皮肾镜取石术患者的术后疼痛和止痛要求的作用。方法：这项随机对照研究是于2011年6月1日至巴基斯坦白沙瓦的Hayatabad Medical Complex肾脏病研究所进行的。 2012年5月31日。共有66例患者（每组33例）通过连续非概率抽样技术纳入研究，并随机分为A组（布比卡因33例）和B组（安慰剂33例）。 A组和分别为32.2 + 2.7和31.09 + 2.6岁。 A和B组的平均手术时间分别为70.66±7.41和72.12±.65分钟。在视觉模拟量表上，A组的总平均疼痛评分为4.15±1.48，而B组的总平均疼痛评分为6.06±1.02（p <0.05）。 A组和B组女性患者的平均疼痛评分分别为4.07（范围2-7）和6.13（范围4-8）。 A组和B组男性患者的平均疼痛评分分别为4.12（范围2-7）和6.0（范围4-7）。在本研究中，ageon疼痛知觉的影响并不显着，因为我们仅包括成年患者（≥14岁），并且在不同年龄组的患者中均观察到混合反应。结论：术前布比卡因对肾造口术的浸润是安全有效的减轻术后疼痛和镇痛要求的方法，避免了阿片类药物或非阿片类药物的镇痛作用。

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