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首页> 外文期刊>Khyber Medical University Journal >EFFECT OF ENDURANCE EXERCISE ON BRAIN NATRIURETIC PEPTIDE (BNP)
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EFFECT OF ENDURANCE EXERCISE ON BRAIN NATRIURETIC PEPTIDE (BNP)

机译：耐力运动对脑钠肽（BNP）的影响

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OBJECTIVE: To evaluate the effect of maximal exercise on the level ofbrain natriuretic peptide (BNP) and cardiac adaptive changes in endurancetrained elite athletes and sedentary healthy subjects.METHODOLOGY: This Cross-sectional comparative study was conductedat Army Medical College in collaboration with Armed ForcesInstitute of Cardiology (AFIC) Rawalpindi. Twenty two elite enduranceathletes (Long Distance Runners) and 22 matching sedentary (from sameunit having no sports activity) controls were selected by convenience(non-probability) sampling technique. Height, body weight, blood pressure,pulse rate and ECG were recorded. The blood was drawn fromantecubital vein for measuring BNP and aldosterone before exerciseand again after exercise. The echocardiography of left ventricle wasdone to measure the end-diastolic internal diameter (LVIDd), diastolicinterventricular septal thickness (IVSTd), and diastolic posterior wallthickness (PWTd). The left ventricular mass (LVM) was calculated byDevereux formula. The data were recorded in a proforma and analyzedby SPSS version 10.RESULTS: It was observed that the heart rate and blood pressure ofathletes were significantly less than the controls (p0.001); while LVIDd,IVST, PWTd, and LVM was greater in athletes than controls (p0.001).Pre-exercise BNP level was 45.29+18.69 pmol/l & 34.16+13.74 pmol/lwhile post-exercise BNP level was 58.32+19.65 pmol/l & 43.638+11.82pmol/l in athletes and controls respectively (p0.01). Pre-exerciseAldosterone level was 15.34+2.77 ng/dl & 13.05+2.134 ng/dl whilepost-exercise BNP level was 16.01+2.14 ng/dl & 14.65+2.30 ng/dl inathletes and controls respectively (p0.01).CONCLUSION: The maximal exercise increases the level of BNP inelite athletes significantly.
机译：目的：评估最大运动量对耐力训练的精英运动员和久坐不动的健康受试者的大脑利钠肽（BNP）水平和心脏适应性变化的影响。心脏病学（AFIC）拉瓦尔品第。通过便利性（非概率）采样技术选择了22名精英耐力运动员（长跑运动员）和22名相匹配的久坐运动员（来自没有运动的同一个单位）。记录身高，体重，血压，脉搏率和心电图。运动前和运动后，从肘静脉取血以测定BNP和醛固酮。超声心动图检查左室舒张末期内径（LVIDd），舒张期室间隔厚度（IVSTd）和舒张后壁厚度（PWTd）。用Devereux公式计算左心室质量（LVM）。数据记录在形式表中，并通过SPSS版本10进行分析。结果：观察到运动员的心率和血压显着低于对照组（p <0.001）;运动员的LVIDd，IVST，PWTd和LVM高于对照组（p <0.001）。运动前BNP水平为45.29 + 18.69 pmol / l和34.16 + 13.74 pmol / l，而运动后BNP水平为58.32 + 19.65 pmol。 / l和43.638 + 11.82pmol / l分别在运动员和对照组中（p <0.01）。运动前和运动后醛固酮水平分别为15.34 + 2.77 ng / dl和13.05 + 2.134 ng / dl，而运动后BNP水平分别为16.01 + 2.14 ng / dl和14.65 + 2.30 ng / dl（p <0.01）。最大程度的运动会显着提高BNP优秀运动员的水平。

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