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首页> 外文期刊>Korean Circulation Journal >Clinical Usefulness of Noninvasive Measurement of Coronary Flow Velocity Reserve with Transthoracic Doppler Echocardiography for Detection of Restenosis after Revascularization of Left Anterior Descending Coronary Artery
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Clinical Usefulness of Noninvasive Measurement of Coronary Flow Velocity Reserve with Transthoracic Doppler Echocardiography for Detection of Restenosis after Revascularization of Left Anterior Descending Coronary Artery

机译：经胸多普勒超声检查无创测量冠状动脉血流速度储备在检测左冠状动脉前降支血管再狭窄后的再狭窄的临床价值

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Background and Objectives The measurement of the coronary flow velocity reserve (CFR) using transthoracic Doppler echocardiography (TTDE) has been reported to be useful for assessing the physiological significance of left anterior descending coronary artery (LAD) stenosis. This study was performed to evaluate the usefulness of CFR by TTDE for diagnosis of restenosis following revascularization procedures. Subjects and Methods Patients who were scheduled for follow-up coronary angiography following percutaneous intervention, or coronary bypass, surgery for a LAD lesion were enrolled. Prior to the follow-up coronary angiography, flow velocities in the distal LAD were measured by TTDE, both at rest and during the intravenous infusion of adenosine. CFR was defined as the ratio of the hyperemic to the basal peak diastolic velocities. Angiographic restenosis was defined as a diameter stenosis of more than 50% of the normal value by a quantitative coronary angiography. Of 142 consecutive patients, measurement of the CFR was possible in 95% (n=135), with 39 patients having a myocardial infarction in the LAD territory. The remaining 96 patients were used as the subjects ofin this study. Results The diameter stenosis was 41±26%, with angiographic restenosis found in 33 patients (34%). The mean CFR by TTDE was 2.5±1.1. CFR Conclusion The noninvasive measurement of the CFR with TTDE is highly feasible, and can be a useful diagnostic modality for restenosis of a LAD following a revascularization procedure.
机译：背景和目的据报道，使用经胸多普勒超声心动图（TTDE）测量冠状动脉血流储备量（CFR）对于评估左冠状动脉前降支（LAD）狭窄的生理意义是有用的。进行这项研究以评估TTDE进行CFR对血运重建术后再狭窄诊断的有用性。受试者和方法招募了计划进行经皮介入治疗或冠状动脉搭桥手术后进行LAD病变手术的冠状动脉造影患者。在随访冠状动脉造影之前，在静息时和静脉内输注腺苷期间，通过TTDE测量远端LAD的流速。 CFR定义为充血与基础舒张峰值速度之比。血管造影再狭窄定义为通过定量冠状动脉血管造影术得出的直径狭窄超过正常值的50％。在142例连续患者中，有95％（n = 135）的患者可以进行CFR测量，其中39例患者在LAD区域患有心肌梗塞。其余96例患者用作本研究的对象。结果直径狭窄为41±26％，其中33例（34％）出现血管造影再狭窄。 TTDE的平均CFR为2.5±1.1。 CFR结论使用TTDE进行CFR的无创测量非常可行，并且可以作为血运重建术后LAD再狭窄的有用诊断方法。

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