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首页> 外文期刊>Kosuyolu Kalp Dergisi >Assessment of Relationship Between Subclinical Atherosclerosis and Benign Prostate Hyperplasia Using Epicardial Fat Thickness and Carotid Intima-Media Thickness
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Assessment of Relationship Between Subclinical Atherosclerosis and Benign Prostate Hyperplasia Using Epicardial Fat Thickness and Carotid Intima-Media Thickness

机译:用心外膜脂肪厚度和颈动脉内膜-中膜厚度评估亚临床动脉粥样硬化和前列腺增生的关系

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Introduction: Benign prostatic hyperplasia (BPH) is the most common disorder in elderly men. Although the relationship between atherosclerosis and BPH is known, the association between subclinical atherosclerosis and BPH has not yet been investigated. The aim of our study was to assess this relationship using carotid intima-media thickness (CIMT). Patients and Methods: Fifty patients with BPH and 50 control subjects without BPH of ages 50-65 years were enrolled. According to the international prostate symptom score (IPSS), which is used for the evaluation of LUTS, patients were divided into mild-moderate (IPSS 20 point, n= 33 patients) and severe groups (IPSS ≥ 20 point, n= 17 patients). CIMT was evaluated using ultrasonography. The relationship between CIMT and other parameters were analysed. Results: CIMT was significantly higher in BPH group (p= 0.02). In addition, it was significantly higher in severe LUTS group in subgroup analyses, which included only patients (1.22 ± 0.3 vs. 0.84 ± 0.2, p 0.001). There was a positive correlation between CIMT and IPSS (r= 0.745, p 0.001). CIMT and HDL cholesterol were found to be independent predictors of BPH in multivariate analysis. Conclusion: Subclinical atherosclerosis and BPH may share common aetiopathogenic factors. Therefore, BPH and lower urinary tract symptoms may be indicators of atherosclerotic burden in men of the same age group.
机译:简介:良性前列腺增生(BPH)是老年男性中最常见的疾病。尽管动脉粥样硬化与BPH之间的关系是已知的,但尚未研究亚临床动脉粥样硬化与BPH之间的关联。我们研究的目的是使用颈动脉内中膜厚度(CIMT)评估这种关系。患者和方法:招募了50名BPH患者和50名年龄在50-65岁之间的无BPH的对照组。根据用于评估LUTS的国际前列腺症状评分(IPSS),将患者分为轻度-中度(IPSS <20分,n = 33位患者)和重度组(IPSS≥20分,n = 17)耐心)。 CIMT使用超声检查进行评估。分析了CIMT与其他参数之间的关系。结果:BPH组CIMT显着升高(p = 0.02)。此外,在亚组分析中,严重LUTS组的患病率明显更高,仅包括患者(1.22±0.3对0.84±0.2,p <0.001)。 CIMT与IPSS之间存在正相关(r = 0.745,p <0.001)。在多变量分析中,发现CIMT和HDL胆固醇是BPH的独立预测因子。结论:亚临床动脉粥样硬化和BPH可能具有共同的致病因素。因此,BPH和下尿路症状可能是同一年龄段男性动脉粥样硬化负担的指标。

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