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首页> 外文期刊>Nepal Journal of Obstetrics and Gynaecology >Identification and Antimicrobial Susceptibility Pattern of Clinically Significant Coagulase-negative Staphylococci
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Identification and Antimicrobial Susceptibility Pattern of Clinically Significant Coagulase-negative Staphylococci

机译：临床上重要的凝固酶阴性葡萄球菌的鉴定和药敏模式

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Aims: This study was undertaken to determine the prevalence and pathogenicity of coagulase-negative staphylococci in clinical samples and to study the antibiotic-sensitivity pattern of the coagulase-negative isolates. Methods: A prospective study was conducted over a period of two years on patients admitted in the Sher-i-Kashmir Institute of Medical Sciences. Blood, urine, pus, catheter tips, cerebrospinal fluid and peritoneal fluid samples of patients who fulfilled the criteria for being labeled as nosocomial were cultured. Results: One hundred and six strains of coagulase negative staphylococci were isolated from the samples and among them 90 isolates were identified as Staphylococcus epidermidis (84.90%). Most of the coagulase-negative staphylococci isolates were resistant to penicillin, cephalosporins and fluoroquinolones. Methicillin resistance was found in a significant number of coagulase-negative isolates. All the isolates were found to be sensitive to vancomycin. Conclusions: The results of the study emphasized that isolation of coagulase-negative staphylococci should be viewed with serious concern and accurate species identification and antimicrobial susceptibility testing should be performed in all cases. DOI: http://dx.doi.org/10.3126jog.v9i2.11769
机译：目的：本研究旨在确定临床样本中凝固酶阴性葡萄球菌的流行和致病性，并研究凝固酶阴性分离株的抗生素敏感性模式。方法：对谢尔-克什米尔医学科学研究所收治的患者进行了为期两年的前瞻性研究。培养符合医院标准的患者的血液，尿液，脓液，导管尖端，脑脊液和腹膜液样品。结果：从样本中分离出116株凝固酶阴性葡萄球菌，其中分离出的90株为表皮葡萄球菌（84.90％）。大多数凝固酶阴性葡萄球菌分离株对青霉素，头孢菌素和氟喹诺酮类耐药。在大量凝固酶阴性分离株中发现了耐甲氧西林。发现所有分离株对万古霉素敏感。结论：研究结果强调应认真关注分离凝固酶阴性葡萄球菌的情况，并在所有情况下均应进行准确的物种鉴定和抗菌药敏试验。 DOI：http：//dx.doi.org/10.3126jog.v9i2.11769

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