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首页> 外文期刊>Kaohsiung Journal of Medical Sciences >Occupational risks of esophageal cancer in Taiwanese men
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Occupational risks of esophageal cancer in Taiwanese men

机译：台湾男性食管癌的职业风险

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This study aims to explore whether certain occupations were associated with the risk of esophageal squamous cell carcinoma (ESCC) in Taiwan. In a hospital-based case-control study, we collected 326 newly diagnosed ESCC patients and 386 age-matched controls (the ratio of case patients: controls?=?1:1–2). All respondents completed a questionnaire, including 33 occupations in which environments potential exposure to cancer-related hazards are present. Workers with dust and metal exposure were categorized into Groups A and B, respectively. Relative risks for ESCC were estimated by odds ratios adjusting for covariates (AOR). Compared with the controls, farmer/gardener (AOR?=?2.08, 95% CI?=?1.02–4.24) and workers in Group A (AOR?=?2.80, 95% CI?=?1.21–6.47) had significantly higher risk for developing ESCC. A tendency of increased risk was also found in workers in group B (OR?=?5.72 95% CI?=?2.33–14.03), but such association was not significant after adjusting for other covariates (AOR?=?1.57, 95% CI?=?0.54–6.61). Our results suggested that farmer/gardener and workers with exposure to dust had a significant excess risk of ESCC. This study added further evidence to the current knowledge that occupational hazards are important in the development of ESCC.
机译：这项研究旨在探讨台湾某些职业是否与食管鳞状细胞癌（ESCC）风险相关。在一项基于医院的病例对照研究中，我们收集了326名新确诊的ESCC患者和386个年龄相匹配的对照（病例患者与对照的比例=？1：1–2）。所有受访者均完成了一份问卷调查，包括33个存在与癌症相关危害潜在暴露环境的职业。灰尘和金属暴露的工人分别分为A组和B组。通过校正协变量（AOR）的优势比估算ESCC的相对风险。与对照组相比，A组的农民/园丁（AOR≥2.08，95％CI≥1.02–4.24）和工人（AOR≥2.80，95％CI≥1.21-6.47）显着高于对照组。发展ESCC的风险。 B组工作人员的风险也有增加的趋势（OR？=？5.72 95％CI？=？2.33-14.03），但在校正其他协变量后，这种关联并不显着（AOR？=？1.57，95％ CI？=？0.54-6.61）。我们的结果表明，暴露于粉尘的农民/园丁和工人的ESCC风险过高。这项研究为当前的知识增加了进一步的证据，即职业危害对ESCC的发展至关重要。

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