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首页> 外文期刊>Neurocirugia >Diagnosis of central nervous system infection by CSF sampling of the myelomeningocele sac as an alternative to ventricular tap
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Diagnosis of central nervous system infection by CSF sampling of the myelomeningocele sac as an alternative to ventricular tap

机译：通过脑脊液囊的脑脊液取样替代心室水龙头诊断中枢神经系统感染

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Background. Infection significantly affects mortality and morbidity in myelomeningocele cases. Ventricular tap is the most common method performed to diagnose central nervous system (CNS) infection in myelomeningocele patients. However, the ventricular tap can cause serious trauma to the baby and to the family. Here we discuss the technique of taking a cerebrospinal fluid (CSF) sample from the sac in myelomeningocele cases. Methods. The study comprised 24 myelomeningocele patients undergoing sac repair; 7 patients in the early period and 17 in the late period (after the first 24 hours). CSF samples were taken from the sac and via ventricular tap. In all patients' samples, cell count and cultures were compared. Results. In patients who underwent early meningomyelocele repair there was no significant difference between sac and ventricular CSF. There were also no positive cultures in samples taken from both areas. In comparison, in the group submitted to late repair, the number of cells in the sac and ventricle CSF samples was over 10 in 4 of the 17 patients. The cultures from CSF samples taken from both areas were positive for E. coli. In 13 of 17 patients who were admitted to our clinic for late repair, there was no significant difference between the number of cells in the sac and in ventricular samples. Cultures taken from these patients were negative. Conclusion. Puncture of the sac represents a quicker and more convenient way to obtain CSF in myelomeningocele cases. In addition, there was no increase in pain to a level that would cause stress for the baby. A CSF sample can be taken from the sac for diagnosis of CNS infection in myelomeningocele patients. This method, therefore, represents a safer and more comfortable option for both the patient and doctor.
机译：背景。感染显着影响脊髓膜膨出病例的死亡率和发病率。心室轻拍是诊断脊髓膜膨出患者中枢神经系统（CNS）感染的最常用方法。但是，心室轻拍会给婴儿和家庭造成严重伤害。在这里，我们讨论了在脊髓膜膨出病例中从囊中提取脑脊液（CSF）样本的技术。方法。该研究包括24名接受囊修复的脊髓膜囊膨出患者。早期7例，晚期17例（头24小时后）。脑脊液样品取自囊并通过心室水龙头。在所有患者的样本中，比较了细胞计数和培养。结果。在接受早期脑膜脊髓膨出修复的患者中，囊和心室CSF之间无显着差异。从这两个地区采集的样品中也没有阳性培养物。相比之下，在接受后期修复的组中，17例患者中有4例的囊和心室CSF样品中的细胞数量超过10。来自两个地区的CSF样品培养物的大肠杆菌均为阳性。在我们诊所接受后期修复的17例患者中，有13例囊和心室样品中的细胞数量没有显着差异。这些患者的培养阴性。结论。在髓鞘膜膨出病例中，穿刺囊是获得脑脊液的一种更快，更方便的方法。此外，疼痛没有增加到会给婴儿带来压力的程度。可以从囊中取出脑脊液样本，以诊断脊髓膜膨出患者的中枢神经系统感染。因此，这种方法对于患者和医生而言都是一种更安全，更舒适的选择。

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