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首页> 外文期刊>Neuropsychiatric Disease and Treatment >The effects of psychiatric treatment on depression, anxiety, quality of life, and sexual dysfunction in patients with inflammatory bowel disease
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The effects of psychiatric treatment on depression, anxiety, quality of life, and sexual dysfunction in patients with inflammatory bowel disease

机译：精神科治疗对炎性肠病患者抑郁，焦虑，生活质量和性功能障碍的影响

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Objective: Depression and anxiety are common disorders in inflammatory bowel disease (IBD). Our aim is to prospectively determine the effect of psychiatric treatment on scores for depression, anxiety, quality of life (QoL), and sexual dysfunction in an outpatient population diagnosed with IBD and also anxiety and/or depression disorder. Patients and methods: Patients who scored higher than the cutoff point on the Hospital Anxiety Depression Scale were referred for further structured psychiatric evaluation and determination of the need for psychiatric drug treatment. Patients who underwent drug therapy completed Short Form-36 (SF-36) and the Arizona Sexual Experience Scale at baseline and after 6?months of follow-up. Results: Major depressive disorder and generalized anxiety disorder were the most common diagnoses. After 6 months, 47 patients had completely adhered to drug treatment (group A), whereas 20 were nonadherent (group B). In group A, all domains of SF-36, Arizona Sexual Experience Scale, depression/anxiety scores, and Crohn’s disease activity index were statistically improved after treatment when compared with the baseline. In group B, the three domains of SF-36, platelet count, and mean corpuscular volume were worse between baseline and at 6 months. Conclusion: In IBD patients having any psychiatric disorder, 6?months of antidepressant drug treatment is associated with an improvement in depression, anxiety, QoL, and sexual functioning scores, as well as an improvement in Crohn’s disease activity index. On the other hand, insufficient psychiatric treatment seems to be related to a poor QoL.
机译：目的：抑郁和焦虑症是炎症性肠病（IBD）的常见疾病。我们的目的是前瞻性确定精神病治疗对诊断为IBD以及焦虑和/或抑郁症的门诊患者的抑郁，焦虑，生活质量（QoL）和性功能障碍得分的影响。患者和方法：将在医院焦虑抑郁量表上得分高于临界点的患者转诊，以进行进一步的结构性精神病学评估和确定是否需要精神病药物治疗。接受药物治疗的患者在基线和随访6个月后完成了Short-36（SF-36）和Arizona性经验量表。结果：重度抑郁症和广泛性焦虑症是最常见的诊断。 6个月后，有47位患者完全坚持药物治疗（A组），而有20位未坚持药物治疗（B组）。在A组中，与基线相比，治疗后SF-36，亚利桑那州性经验量表，抑郁/焦虑评分和克罗恩病活动指数的所有方面均得到统计学改善。 B组中，基线和6个月时SF-36，血小板计数和平均红细胞体积这三个区域较差。结论：对于患有任何精神疾病的IBD患者，抗抑郁药物治疗6个月可改善抑郁，焦虑，生活质量和性功能评分，并改善克罗恩病活动指数。另一方面，精神病治疗不足似乎与生活质量较差有关。

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