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首页> 外文期刊>Neurosurgical focus >Nasal symptoms following endoscopic transsphenoidal pituitary surgery: assessment using the General Nasal Patient Inventory
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Nasal symptoms following endoscopic transsphenoidal pituitary surgery: assessment using the General Nasal Patient Inventory

机译:内镜经蝶窦垂体手术后的鼻部症状:使用一般鼻科患者清单进行评估

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Object The endoscopic approach for pituitary tumors is a recent innovation and is said to reduce the nasal trauma associated with transnasal transsphenoidal surgery. The authors assessed the temporal changes in the rhinological symptoms following endoscopic transsphenoidal surgery for pituitary lesions, using the General Nasal Patient Inventory (GNPI). Methods The GNPI was administered to 88 consecutive patients undergoing endoscopic transsphenoidal surgery at 3 time points (presurgery, 3–6 months postsurgery, and at final follow-up). The total GNPI score and the scores for the individual GNPI questions were calculated and differences between groups were assessed once before surgery, several months after surgery, and at final follow-up. Results Of a maximum possible score of 135, the mean GNPI score at 3–6 months postsurgery was only 12.9 ± 12 and was not significantly different from the preoperative score (10.4 ± 13) or final follow-up score (10.3 ± 10). Patients with functioning tumors had higher GNPI scores than those with nonfunctioning tumors for each of these time points (p Conclusions Endoscopic transsphenoidal surgery is a well-tolerated minimally invasive procedure for pituitary fossa lesions. Overall patient-assessed nasal symptoms do not change, but some individual symptoms may show a mild worsening or overall improvement.
机译:目的垂体瘤的内窥镜治疗是一项最新创新,据说可以减少与经鼻经蝶窦手术相关的鼻外伤。作者使用鼻总患者清单(GNPI)评估了经内镜经蝶窦手术治疗的垂体病变后的流变学症状随时间的变化。方法GNPI在3个时间点(手术前,手术后3-6个月以及最后的随访时间)内接受连续88例接受内镜经蝶窦手术的患者。计算总GNPI得分和单个GNPI问题的得分,并在手术前,手术后几个月以及最终随访时评估组之间的差异。结果在最高可能得分135中,术后3-6个月的GNPI平均得分仅为12.9±12,与术前得分(10.4±13)或最终随访得分(10.3±10)并无显着差异。在所有这些时间点上,具有功能性肿瘤的患者均比无功能性肿瘤的患者具有更高的GNPI评分(结论结论内镜经蝶窦手术是一种对垂体窝病变耐受良好的微创手术。总体而言,患者评估的鼻部症状没有改变,但有些个别症状可能显示轻度恶化或总体改善。

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