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首页> 外文期刊>Nigerian Journal of Physiological Sciences >Baseline Haematology and Erythrocyte Morphological Changes of Apparently Normal Dogs Raised in Ibadan, Oyo State
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Baseline Haematology and Erythrocyte Morphological Changes of Apparently Normal Dogs Raised in Ibadan, Oyo State

机译：奥约州伊巴丹饲养的正常狗的基线血液学和红细胞形态变化

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Summary: This study evaluates the haematological parameters and the observed erythrocytes morphological changes?in dogs raised in Ibadan, Oyo State in the south western part of Nigeria. Blood samples were collected from sixty-four apparently healthy dogs. The haematological parameters of the blood samples collected were evaluated with the quantification of the percentage erythrocyte morphological abnormalities. The result of the quantitative count of the erythrocyte morphological abnormalities were also converted using reference guide to give the numerical/descriptive clinical grade of the associated morphological abnormalities. There was a significant difference between the haematological parameters reported in this study and the commonly used dog haematological reference ranges from temperate regions used in laboratories in Nigeria. Some of the morphological abnormalities observed in this study include echinocyte (4.12±0.35%), macrocyte (2.61±0.22%) and spherocyte (2.17±0.29%) and eccentrocyte (0.39±0.06%) while other such as acanthocyte (1.39±0.19), leptocyte (0.71±0.13), schizocyte (0.703±0.104) and codocyte (0.50±0.11) were also seen. These study findings show that the associated morphological changes were all not significant and fall within the acceptable range using the reference guide for erythrocyte morphological abnormalities even when the haematological values differ significantly from?the reference value. This study provides baseline information on the haematological parameters and the novel correlation of the associated erythrocyte abnormalities seen as a corresponding proof of the apparently healthy status of the dogs raised in Ibadan used for this study. The study while serving as an important means of verification of the reference range of haematological parameters also shows that clinical case interpretation using haematological baseline data from the temperate region should be used with caution in our tropical environment. This thus necessitates the need for an advocacy to build a reference range of haematological parameters that can be used as a working baseline value for the tropical environment. Keywords: Haematological parameters, Erythrocyte morphological changes, South Western Nigeria
机译：摘要：本研究评估了尼日利亚西南部奥约州伊巴丹市饲养的狗的血液学参数和观察到的红细胞形态变化。从六十四只看上去健康的狗身上采集血液样本。通过定量红细胞形态异常百分比来评估所收集的血液样品的血液学参数。还使用参考指南转换了红细胞形态异常的定量计数结果，以给出相关形态异常的数值/描述性临床评分。在这项研究中报道的血液学参数与尼日利亚实验室中温带地区常用的狗血液学参考范围之间存在显着差异。在这项研究中观察到的一些形态异常包括棘突细胞（4.12±0.35％），大细胞（2.61±0.22％）和球细胞（2.17±0.29％）和离心细胞（0.39±0.06％），而其他诸如棘突细胞（1.39±0.19） ），还观察到瘦细胞（0.71±0.13），分裂细胞（0.703±0.104）和鳕鱼细胞（0.50±0.11）。这些研究结果表明，即使血液学值与参考值有显着差异，使用红细胞形态学异常的参考指南，相关的形态学变化也不是很明显并且落在可接受的范围内。这项研究提供了有关血液学参数的基线信息，以及相关的红细胞异常的新颖相关性，这些信息被视为该研究使用的伊巴丹养狗的明显健康状况的相应证据。该研究虽然是验证血液学参数参考范围的重要手段，但也表明在热带环境中，应谨慎使用温带地区血液学基线数据进行临床病例解释。因此，这就需要倡导建立可以用作热带环境工作基准值的血液学参数参考范围。关键词：血液学参数;红细胞形态变化;尼日利亚西南

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