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Intraoperative stimulation techniques for functional pathway preservation and glioma resection

机译:术中刺激技术用于功能通路保存和神经胶质瘤切除术

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Although a primary tenet of neurosurgical oncology is that survival can improve with greater tumor resection, this principle must be tempered by the potential for functional loss following a radical removal. Preoperative planning with functional and physiological imaging paradigms, combined with intraoperative strategies such as cortical and subcortical stimulation mapping, can effectively reduce the risks associated with operating in eloquent territory. In addition to identifying critical motor pathways, these techniques can be adapted to identify language function reliably. The authors review the technical nuances of intraoperative mapping for low- and high-grade gliomas, demonstrating their efficacy in optimizing resection even in patients with negative mapping data. Collectively, these surgical strategies represent the cornerstone for operating on gliomas in and around functional pathways.
机译:尽管神经外科肿瘤学的主要原则是,随着肿瘤切除的增加,生存率可以提高,但是必须根除根治后可能丧失功能的可能性,以此来调节这一原则。具有功能和生理成像范例的术前计划,结合术中策略(例如皮层和皮层下刺激图),可以有效降低在雄辩区域进行手术的风险。除了识别关键的运动路径外,这些技术还可用于可靠地识别语言功能。作者回顾了低级和高级别神经胶质瘤术中作图的技术细微差别,证明了即使在阴性作图数据的患者中,它们也能优化切除效果。总的来说,这些手术策略代表了在功能途径中及其周围对神经胶质瘤进行手术的基石。

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