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首页> 外文期刊>Nucleus >Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis
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Moving and stopping: Regulation of chromosome movement to promote meiotic chromosome pairing and synapsis

机译：移动和停止：调节染色体移动以促进减数分裂染色体配对和突触

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Meiosis is a specialized cellular division occurring in organisms capable of sexual reproduction that leads to the formation of gametes containing half of the original chromosome number. During the earliest stage of meiosis, prophase I, pairing of homologous chromosomes is achieved in preparation for their proper distribution in the coming divisions. An important question is how do homologous chromosomes find each other and establish pairing interactions. Early studies demonstrated that chromosomes are dynamic in nature and move during this early stage of meiosis. More recently, there have been several studies across different models showing the conserved nature and importance of this chromosome movement, as well as the key components involved in chromosome movement. This review will cover these major findings and also introduce unexamined areas of regulation in meiotic prophase I chromosome movement.
机译：减数分裂是发生在能够进行有性生殖的生物体中的一种特殊的细胞分裂，导致形成含有原始染色体数目一半的配子。在减数分裂的最早阶段，即前期I，实现了同源染色体的配对，为它们在以后的分裂中的适当分布做准备。一个重要的问题是同源染色体如何相互发现并建立配对相互作用。早期研究表明，染色体在减数分裂的这一早期阶段具有自然的动态和移动性。最近，对不同模型进行了数项研究，显示了这种染色体运动的保守性质和重要性，以及参与染色体运动的关键成分。这篇综述将涵盖这些主要发现，还将介绍减数分裂前期I染色体运动的未检查调控区域。

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