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Lipid-lowering properties of protein-rich mucuna product

机译：富含蛋白质的粘液产品的降脂性能

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Background The objective of this study is to evaluate the effect of protein-rich mucuna product (PRMP) on lipid parameters of hyperlipidemic rats. Methods Hyperlipidemia was induced in male rats for 3 weeks through high-fat diet. After induction, 30 hyperlipidemic rats were divided into five groups of six rats: control group (CG) received casein and four groups received PRMP as protein source at different proportions: 8.2, 16.4, 24.6, and 32.8 % corresponding, respectively, to 25, 50, 75, and 100 % substitution of casein in the diet for 3 weeks. Lipid and oxidative stress parameters of rats were assessed. Results There were no significant differences in food intake and body weight loss among the experimental groups. The concentrations of the serum low-density lipoprotein cholesterol, total cholesterol, and triglycerides were lower in groups fed on PRMP 50, 75, and 100 % than in the CG group ( p Conclusions These findings demonstrated that PRMP exerts hypolipidemic effect; it has a metabolic effect on endogenous cholesterol metabolism and a protector effect on the development of hepatic steatosis. Our results also suggest that PRMP could manage metabolic diseases associated with oxidative stress.
机译：背景技术这项研究的目的是评估富含蛋白质的粘液产品（PRMP）对高脂血症大鼠脂质参数的影响。方法高脂饮食诱导雄性大鼠高脂血症3周。诱导后，将30只高脂血症大鼠分为5组，每组6只：对照组（CG）接受酪蛋白，四组接受PRMP作为蛋白质来源，比例不同，分别为8.2％，16.4％，24.6％和32.8％，分别为25％，饮食中酪蛋白的50％，75％和100％替代3周。评估大鼠的脂质和氧化应激参数。结果实验组的食物摄入量和体重减轻没有显着差异。饲喂PRMP 50％，75％和100％的组的血清低密度脂蛋白胆固醇，总胆固醇和甘油三酸酯的浓度低于CG组（p结论）这些发现表明PRMP具有降血脂作用，具有降血脂作用。代谢对内源性胆固醇代谢的影响以及对肝脂肪变性发展的保护作用我们的结果还表明PRMP可以控制与氧化应激相关的代谢疾病。

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