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Cell surface proteins play an important role in probiotic activities of Lactobacillus reuteri

机译：细胞表面蛋白在罗伊氏乳杆菌的益生菌活性中起重要作用

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Background Eight Lactobacillus reuteri strains, previously isolated from breast-fed human infant feces, were selected to assess the potential contribution of their surface proteins in probiotic activity. These strains were treated with 5?M LiCl to remove their surface proteins, and their tolerance to simulated stomach-duodenum passage, cell surface characteristics, autoaggregation, adhesion, and inhibition of pathogen adhesion to Caco-2 cells were compared with untreated strains. Results The survival rates, autoaggregation, and adhesion abilities of the LiCl-treated L. reuteri strains decreased significantly ( p Conclusions The results revealed that the cell surface proteins of L. reuteri play an important role in their survivability, adhesion, and competitive exclusion of pathogen to epithelial cells.
机译：背景技术选择了八种先前从母乳喂养的人类婴儿粪便中分离出来的罗伊氏乳杆菌菌株，以评估其表面蛋白在益生菌活性中的潜在作用。用5？M LiCl处理这些菌株以去除其表面蛋白，并将它们对模拟的胃－十二指肠通过，细胞表面特征，自动聚集，粘附以及病原体对Caco-2细胞粘附的耐受性与未处理的菌株进行了比较。结果经LiCl处理的罗伊氏杆菌菌株的存活率，自聚集性和粘附能力明显降低（p结论结论表明，罗伊氏杆菌的细胞表面蛋白在它们的存活，粘附和竞争排斥中发挥重要作用。病原体上皮细胞。

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