Abstract:Objective To investigate the effect of multidimensional systematic care on pregnancy outcome and disease awareness of patients with intrahepatic cholestasis of pregnancy (ICP). Methods A total of 82 ICP patients were randomly divided into two groups, with 41 cases in each group. Both two groups were given routing nursing care, and the observation group was applied with multidimensional systematic care. The disease awareness of patients was assessed before and after intervention. Clinical parameters including serum total bilirubin, serum bile acid and alanine aminotransferase, as well as pregnancy outcomes were compared between two groups. Results Patients in the observation group had higher disease awareness compared with those in the control group after nursing intervention(P<0.01). Levels of serum total bilirubin, serum bile acid and alanine aminotransferase were lower in the observation group than those in the control group after nursing intervention (P<0.05). The incidence of fetal distress, premature delivery, amniotic fluid contamination, cesarean section and postpartum hemorrhage were lower in the observation group than those in the control group, with significant difference (P<0.05). Conclusion sMultidimensional systematic care used in ICP patients can significantly increase disease awareness and improve pregnancy outcome.
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