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首页> 外文期刊>Nursing of intrgrated traditional Chinese and Western medicine(Zhong-Xiyi Jiehe Huli ) >右美托咪定在重型颅脑损伤患者中的应用及护理
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右美托咪定在重型颅脑损伤患者中的应用及护理

机译：右美托咪定在重型颅脑损伤患者中的应用及护理

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Abstract：Objective To analyze the application efficacy of dexmedetomidine in the patients with severe craniocerebral injury, and to summarize corresponding nursing measures. Methods The clinical data of 63 patients with severe craniocerebral injury who received dexmedetomidine for sedation and analgesia were retrospectively analyzed. The condition of respiration, heart rate, blood pressure and acroteric oxygen saturation fluctuation of patients were observed during application of dexmedetomidine. Results 〓After application of dexmedetomidine, the restlessness got better. A small dose of midazolam or propofol was combined for the patients with invasive respirator if necessary, there was no obvious man-machine counteraction, and the heart rate and blood pressure fluctuation became stable compared with pre-sedation. The heart rate of 7 out of 63 patients decreased less than 60 times per minute, but got better after reduced administration speed. All the patients didn't suffer from respiratory depression obviously. Conclusion 〓Moderate dose of dexmedetomidine in patients with severe craniocerebral injury for sedation and analgesia can reduce the restlessness, decrease intracranial pressure and cerebral metabolic rate of oxygen, inhibit sympathetic storm, and improve prognosis and quality of life in combination of corresponding nursing measures.
机译：摘要：目的分析右美托咪定在重型颅脑损伤中的应用效果，并总结相应的护理措施。方法回顾性分析63例右美托咪定镇静镇痛的重型颅脑损伤患者的临床资料。在使用右美托咪定期间观察患者的呼吸情况，心率，血压和上肢动脉血氧饱和度波动。结果〓应用右美托咪定后，躁动得到改善。必要时，对于有创呼吸器的患者，应合并小剂量咪达唑仑或丙泊酚，无明显的人机交互作用，与镇静前相比，心率和血压波动稳定。 63位患者中有7位的心率每分钟下降少于60次，但在降低给药速度后好转。所有患者均未明显出现呼吸抑制。结论〓适量右美托咪定可减轻镇静和镇痛作用，对重度颅脑损伤患者具有缓解躁动，降低颅内压和脑氧代谢率，抑制交感神经风暴的作用，并结合相应的护理措施可改善预后和生活质量。

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