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Antraciclinas y síndrome QT prolongado adquirido. Presentación de un caso

机译:蒽环类和获得性长QT综合征。案件介绍

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Acquired long QT syndrome results from secondary causes and can be caused by more than 100 non-antiarrhythmic drugs. Cardiac arrest due to Torsades de pointes induced by drugs causing prolonged QT syndrome is a rare but potentially fatal event, even in hospitals. The case of a 47-year-old patient diagnosed with non-Hodgkin lymphoma admitted to the hematology department of the Dr. Gustavo Aldereguía Lima University General Hospital in Cienfuegos is presented. The patient had been previously treated with anthracyclines and developed episodes of palpitations and syncope later. The treatment included monitoring the patient, avoiding other QT prolonging agents and administrating magnesium sulfate and potassium chloride with a proper maintenance of the fluid and acid-base balance. The presentation of this case aims at motivating interest in new reports on the subject and establishing a direct causal relationship through the evidence provided by new experiences.
机译:获得性长QT综合征是由继发原因引起的,并且可能由100多种非抗心律不齐药物引起。导致QT综合征延长的药物引起的尖尖扭转性心跳骤停是罕见的,但即使在医院也可能致命。介绍了一名在西恩富戈斯的利马大学古斯塔沃·阿尔德雷吉亚·利马大学总医院血液科住院的确诊为非霍奇金淋巴瘤的47岁患者的病例。该患者先前曾接受蒽环类药物治疗,后来出现心pit发作和晕厥。治疗包括监测患者,避免使用其他QT延长剂以及在适当维持体液和酸碱平衡的基础上给予硫酸镁和氯化钾。本案例的介绍旨在激发人们对该主题的新报告的兴趣,并通过新经验提供的证据建立直接因果关系。

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