• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Lung India >Role of percutaneous closed needle pleural biopsy among patients of undiagnosed exudative pleural effusion
【24h】

Role of percutaneous closed needle pleural biopsy among patients of undiagnosed exudative pleural effusion

机译：经皮穿刺闭合性胸膜穿刺活检在未诊断渗出性胸腔积液患者中的作用

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background:Sometimes etiological diagnosis of pleural effusion is difficult despite cytological, biochemical and microbiological tests and labeled as undiagnosed exudative pleural effusions.Aim of present study was to make an etiological diagnosis of pleural effusion.Materials and Methods:Study group included patients of exudative pleural effusion where etiological diagnosis could not be yielded by conventional cytological, biochemical and microbiological investigations. Pleural tissue was obtained by Cope’s pleural biopsy needle and or thoracoscopy. Pleural biopsy was subjected to histopathology, ZN staining and culture to find the mycobacterium tuberculosis.Results:Out of 25 patients, 17 (68%) and 8 (32%) were male and female, respectively. Age ranged from 15 to 65 years (mean 31.72). Mean value of serum and pleural fluid LDH was 170.56 U/L and 1080.28 U/L, respectively. Histopathology of 9 (36%) showed epitheloid granuloma with caseation necrosis. In other 9 (36%) patients, epitheloid granulomas (with or without giant cells) was reported. In 5 (20%) patients, histopathology report was of nonspecific chronic inflammation. Histopathology was reported as normal in one case; it turned out to be a case of malignancy. In two (8%) patients, pleural tissue obtained was inadequate for opinions; however, other tests revealed malignancy in one and tuberculosis in other. Ziehl-Neelsen (ZN) stain was positive for AFB in two patients and culture of pleural tissue showed presence of Mycobacterium tuberculosis in three patients.Conclusions:The role of percutaneous closed needle biopsy of pleura among patients of undiagnosed exudative pleural effusion is still accepted as a diagnostic tool, as this may lead to a specific diagnosis among 76% of cases. This is of particular importance in a developing country like India where the facilities of thoracoscopy and imaging guided cutting needle biopsies are not easily available.
机译：背景：尽管进行了细胞学，生化和微生物学检查并标记为未诊断的渗出性胸腔积液，有时仍难以对病因进行胸膜积液的诊断。本研究的目的是对病因进行诊断。常规细胞学，生化和微生物学研究无法得出病因诊断的积液。胸膜组织通过Cope的胸膜活检针和/或胸腔镜检查获得。结果：25例患者中，男性17例（68％），女性8例（32％），结核分枝杆菌经组织病理学，ZN染色和培养发现结核分枝杆菌。年龄范围为15至65岁（平均31.72）。血清和胸水LDH的平均值分别为170.56 U / L和1080.28 U / L。 9例（36％）的组织病理学表现为上皮肉芽肿伴干酪样坏死。在其他9名（36％）患者中，报告了上皮肉芽肿（有或没有巨细胞）。在5名（20％）患者中，组织病理学报告为非特异性慢性炎症。据报道1例组织病理学正常。原来是恶性肿瘤。在两名（8％）患者中，获得的胸膜组织不足以征求意见。然而，其他测试显示，一个肿瘤为恶性肿瘤，而另一个为结核病。 Ziehl-Neelsen（ZN）染色2例AFB阳性，并且胸膜组织培养显示3例存在结核分枝杆菌。结论：未经诊断的渗出性胸腔积液患者的经皮胸膜穿刺活检对胸膜的作用仍被接受一种诊断工具，因为这可能导致76％的病例进行具体诊断。在像印度这样的发展中国家，胸腔镜检查和成像引导的切割针活检设备不易获得，这一点尤其重要。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号