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首页> 外文期刊>Lung India >Predictors of asthma-chronic obstructive pulmonary disease overlap syndrome in patients with chronic obstructive pulmonary disease from a tertiary care center in India
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Predictors of asthma-chronic obstructive pulmonary disease overlap syndrome in patients with chronic obstructive pulmonary disease from a tertiary care center in India

机译:来自印度三级护理中心的慢性阻塞性肺疾病患者的哮喘-慢性阻塞性肺疾病重叠综合征的预测因子

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Background: There is dearth of literature on asthma-chronic obstructive pulmonary disease overlap syndrome (ACOS) in India. The aim was to compare clinical characteristics between patients with ACOS and non-ACOS COPD and to identify clinical predictors of ACOS in patients with COPD. Methods: We conducted a retrospective study by reviewing data collected from patients performing spirometry at our hospital. Those with postbronchodilator FEV1/FVC 1or FVC by 12% and 200 ml postbronchodilator) were diagnosed with ACOS and the rest were considered to have non-ACOS COPD. Data on the 2 groups were compared and statistical analysis was performed. Results: Out of a total of 324 patients, 100 of them had postbronchodilator FEV1/FVC P P = 0.02) and ankle edema (P P = 0.01) with lower smoking index (P = 0.03), and had frequent (≥2) ER visits (P = 0.04). However, very frequent (≥3 per year) hospital admissions (P P = 0.02), and pulmonary hypertension diagnosed by two-dimensional echocardiography (P Conclusion: Our study highlights how the ACOS phenotype may clinically differ from their counterparts elsewhere, making it a clinical challenge to identify them in India.
机译:背景:印度缺乏关于哮喘-慢性阻塞性肺疾病重叠综合征(ACOS)的文献。目的是比较ACOS和非ACOS COPD患者的临床特征,并确定COPD患者ACOS的临床预测指标。方法:我们通过回顾从我院进行肺活量测定的患者收集的数据进行了回顾性研究。那些支气管扩张剂后FEV 1 / FVC 1 或FVC分别为12%和支气管扩张剂后剂量为200 ml的患者被诊断出患有ACOS,其余患者被认为是非ACOS COPD。比较两组的数据并进行统计分析。结果:在总共324例患者中,有100例具有较低的吸烟指数(P = 0.03)的支气管扩张剂后FEV 1 / FVC PP = 0.02)和踝部水肿(PP = 0.01)。频繁(≥2)急诊就诊(P = 0.04)。然而,非常频繁的住院(每年≥3)(PP = 0.02),以及通过二维超声心动图诊断出的肺动脉高压(P结论):我们的研究强调了ACOS表型在临床上可能与其他地方的同行不同,从而使其成为临床挑战以在印度识别他们。

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