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首页> 外文期刊>Research Journal of Medical Sciences >Positivity for Anti-HCV Antibodies among Italian Hospitalized Patients
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Positivity for Anti-HCV Antibodies among Italian Hospitalized Patients

机译：意大利住院患者中抗HCV抗体的阳性率

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To assess the prevalence of anti Hepatitis C Virus antibodies (anti-HCV) in patients admitted to a primary hospital, far beyond a decade from hepatitis C virus discovery. Six hundred and four consecutive patients (307 female), admitted to the medical ward of Roccadaspide hospital during the year 2002 were studied. Firstly, all the enrolled subjects were examined for the anti-HCV. Secondly, the anti-HCV positive patients were screened for the qualitative HCV-RNA. Finally, the HCV-RNA positive patients were tested for viral load and HCV genotype. Among the patients enrolled, 43 (7.12%) tested reactive for anti-HCV, without difference between sexes. Thirty two of these subjects (74.4%) were unaware of their condition. Among the anti-HCV positive subjects, 81.4% came out to be HCV-RNA positive (18/25 males, 72.0% and 17/18 females, 94.4%). Predominant genotypes were 1b and 2a/2c (54.3 and 34.3%, respectively); more uncommon resulted to be 1a (8.6%) and 3a genotypes (2.8%).
机译：为了评估抗丙型肝炎病毒抗体（抗-HCV）在一家基层医院住院患者的患病率，距发现丙型肝炎病毒已有十多年了。研究了2002年入Roccadaspide医院内科病房的604例患者（307例女性）。首先，检查所有入选受试者的抗HCV。其次，筛选抗HCV阳性的患者的定性HCV-RNA。最后，对HCV-RNA阳性患者的病毒载量和HCV基因型进行了测试。在入组的患者中，有43名（7.12％）对抗HCV有反应，没有性别差异。这些受试者中有32名（74.4％）没有意识到他们的病情。在抗HCV阳性受试者中，有81.4％为HCV-RNA阳性（男性18/25，72.0％，女性17/18，94.4％）。主要基因型为1b和2a / 2c（分别为54.3％和34.3％）;更罕见的是1a（8.6％）和3a基因型（2.8％）。

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