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The Role of DNA in Forensic Odontology (Part I) DNA Analysis Methods

机译:DNA在法医牙医学中的作用(第一部分)DNA分析方法

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During the last years, DNA analysis methods are applied to forensic cases. Also, forensic dental record comparison has been used for human identification in cases where destruction of bodily tissues or prolonged exposure to the environment has made other means of identification impractical, i.e., after fire exposure, aircraft inflammation or mass disasters. Dental DNA represent an excellent source of genomic DNA. The interest in using dental tissues as a DNA-source of individual identification falls within the particular character of resistance of this organ towards physical or chemical exterior aggressions. DNA can be used for determination of the found remains identity. The identification of individuals is not the only use for DNA. The technique has allowed criminal investigators to link victims to crime scenes once the body has been removed and incinerated. Therefore, it is prudent for the forensic odontologist to become familiar with the DNA analysis methods. The purpose of the Part I of this report is to review of the DNA structure and explain of some common terms which are used for the description of current methods of DNA analysis. Furthermore, the importance of mitochondrial DNA is reported because of its difference from the nuclear or chromosomal DNA in a number of ways that make it an attractive alternative for forensic analysis.
机译:在最近几年中,DNA分析方法被应用于法医案件。另外,在身体组织的破坏或长时间暴露于环境使其他鉴定手段变得不切实际的情况下,即在着火,飞机发炎或大灾难之后,法医牙科记录比较已用于人类鉴定。牙科DNA是基因组DNA的极佳来源。使用牙科组织作为个体识别的DNA源的兴趣在于该器官对物理或化学外部侵略的抵抗力的特定特征。 DNA可用于确定发现的遗骸身份。识别个人并不是DNA的唯一用途。一旦尸体被移走并焚化,该技术使犯罪调查人员能够将受害者与犯罪现场联系起来。因此,法医牙医师应熟悉DNA分析方法。本报告第一部分的目的是回顾DNA结构并解释一些用于描述当前DNA分析方法的常用术语。此外,由于线粒体DNA与核DNA或染色体DNA的差异,在许多方面也有所报道,这使其成为法医分析的有吸引力的替代方法。

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